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Antithrombotic Drug Therapy in Cardiovascular Disease

  • Book
  • © 2010

Overview

Editors:
  1. Arman T. Askari

    1. Western Reserve Heart Care, Hudson, U.S.A.

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    You can also search for this editor in PubMed   Google Scholar

  2. A. Michael Lincoff

    1. Dept. Cardiovascular Medicine, Cleveland Clinic, Cleveland, U.S.A.

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  • Comprehensive overview of the pathophysiology, including the genetics, of arterial and venous thrombosis
  • Detailed, up-to-date data regarding the use of the currently available antithrombotic therapies for commonly-encountered clinical situations in Cardiology
  • Provides rapid access to instructional discussions of various therapies
  • Includes supplementary material: sn.pub/extras

Part of the book series: Contemporary Cardiology (CONCARD)

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Table of contents (24 chapters)

  1. Front Matter

    Pages i-xi
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  2. Basic Principles

    1. Front Matter

      Pages 1-1
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    2. Platelets in Arterial Thrombosis

      • Edward F. Plow, Peter Kelly
      Pages 3-17

    3. The Role of Coagulation in Arterial and Venous Thrombosis

      • Kandice Kottke-Marchant
      Pages 19-38

    4. The Link Between Inflammation and Thrombosis

      • John H. Cleator, Mark Robbins
      Pages 39-61

    5. The Genetics of Thrombosis

      • Svati H. Shah, Richard C. Becker
      Pages 63-114

  3. Antithrombotic Therapy for Stable Coronary Atherosclerotic Disease

    1. Front Matter

      Pages 116-116
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    2. Aspirin in Primary and Secondary Prevention of Cardiovascular Disease

      • Jinesh Kochar, J. Michael Gaziano
      Pages 117-129

    3. Thienopyridines in Stable Coronary Disease

      • Marcus D. Flather, Dipak Kotecha
      Pages 131-141

  4. Antithrombotic Therapy for NSTE ACS

    1. Front Matter

      Pages 144-144
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    2. Antiplatelet Therapies in Unstable Angina and Non-ST Segment Elevation Myocardial Infarction

      • Saif Anwaruddin, Deepak L. Bhatt
      Pages 145-163

    3. Unfractionated Heparin and Enoxaparin for the Management of Non-ST-Segment Elevation Acute Coronary Syndromes

      • Pierluigi Tricoci, Kenneth W. Mahaffey
      Pages 165-181

    4. Direct Thrombin Inhibitors in Acute Coronary Syndromes

      • Tyler L. Taigen, James E. Harvey, A. Michael Lincoff
      Pages 183-201

    5. Synthetic Factor Xa Inhibition in Acute Coronary Syndromes

      • Michael S. Kim, Robert L. Page, Ivan P. Casserly
      Pages 203-215

  5. Antithrombotic Therapy for STEMI

    1. Front Matter

      Pages 219-219
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    2. Antiplatelet Therapies: Aspirin, Clopidogrel and Thienopyridines, and Glycoprotein IIb/IIIa Inhibitors for the Management of ST-Segment Elevation Myocardial Infarction

      • Rory B. Weiner, Marc S. Sabatine
      Pages 219-233

    3. Antithrombin Therapy for Acute ST-Segment Elevation Myocardial Infarction

      • John M. Galla, Arman T. Askari
      Pages 235-246

    4. Fibrinolysis and Facilitated PCI

      • Ryan D. Christofferson, Sorin J. Brener
      Pages 247-257

  6. Antithrombotic Therapy in Interventional Cardiology

    1. Front Matter

      Pages 260-260
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    2. Antithrombotic Therapy in Percutaneous Coronary Intervention

      • Adrian W. Messerli
      Pages 261-282
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Keywords

About this book

Substantial morbidity and mortality remains associated with thrombotic events has stimulated the rapid expansion of the available armamentarium to combat pathologic thrombosis. Pathologic thrombosis plays an essential role in the pathogenesis of acute coronary syndromes (ACS), ischemic complications of percutaneous coronary intervention (PCI), venous thromboembolic disease, and embolic complications of arrhythmias and various cardiomyopathies.

Written by experts in the field, Antithrombotic Drug Therapy in Cardiovascular Disease carefully examines individual and various combinations of the available antithrombotic regimens including fibrinolytic agents, antiplatelet therapies (aspirin, thieneopyridines, glycoprotein IIb/IIIa inhibitors), and anticoagulant therapies (unfractionated heparin, low-molecular-weight heparins, direct thrombin inhibitors, and synthetic factor X inhibitors), non-ST-segment elevation (NSTE) ACS and ST-segment elevation myocardial infarction (STEMI). A detailed overview, Antithrombotic Drug Therapy in Cardiovascular Disease presents the evidence demonstrating the efficacy of available antithrombotic therapies in specific disease states such as atrial fibrillation, cardiomyopathy, valvular heart disease, and heparin-induced thrombocytopenia (HIT).

Reviews

From the reviews: Despite substantial therapeutic progress, considerable morbidity and mortality remains associated with thrombotic events but rapid expansion of the available armamentarium to combat pathologic thrombosis is nicely summarized in this excellent new book which becomes a valuable guide to improved therapy. The experts from the field, selected by its editors, survey individual and various combinations of the available antithrombotic regimens including fibrinolytic agents, antiplatelet therapies (aspirin, thieneopyridines, glycoprotein IIb/IIIa inhibitors), and anticogulant therapies (unfractionated heparin, low-molecular-weight heparins, direct thrombin inhibitors, and synthetic factor X inhibitors). The treatments discussed are up-to-date methods for management of common cardiovascular thrombotic problems designed for appropriate clinical use. Numerous illustrations, tables and figures throughout the book become particularly helpful for the reader. There are seven major divisions covered by twenty four chapters; most of which are multi-authored and include: Basic Principles, Antithrombotic Therapy for Stable Coronary Atherosclerotic Disease, Antithrombotic Therapy for NSTE ACS, Antithrombotic Therapy for STEMI. Antithrombotic Therapy in Interventional Cardiology, Antithrombotic Therapy in Venous Thromboembolism, and Clinical Considerations. The coagulationist should find this text to be a valuable addition to his/her office reference book shelf. William H Wehrmacher MD FACP FACC Harry L Messmore MD FACP from Comprehensive Therapy - 2010 “The chapter authors of this multiauthored book on antithrombotic drug therapy in cardiovascular disease are national and international thought leaders in their respective fields. … The intended audience includes medical students, allied health professionals, physicians in training, and cardiovascular physicians. … This will be a valuable resource for healthcare providers in the field of cardiovasculardisease management. The authors have met their objective of providing a high quality, evidence-based review of this field.” (Timir Paul, Doody’s Review Service, March, 2009)

Editors and Affiliations

  • Western Reserve Heart Care, Hudson, U.S.A.

    Arman T. Askari

  • Dept. Cardiovascular Medicine, Cleveland Clinic, Cleveland, U.S.A.

    A. Michael Lincoff

Bibliographic Information

  • Book Title: Antithrombotic Drug Therapy in Cardiovascular Disease

  • Editors: Arman T. Askari, A. Michael Lincoff

  • Series Title: Contemporary Cardiology

  • DOI: https://doi.org/10.1007/978-1-60327-235-3

  • Publisher: Humana Totowa, NJ

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Humana Press 2010

  • Hardcover ISBN: 978-1-60327-234-6Published: 18 November 2009

  • Softcover ISBN: 978-1-62703-797-6Published: 20 October 2014

  • eBook ISBN: 978-1-60327-235-3Published: 20 March 2010

  • Series ISSN: 2196-8969

  • Series E-ISSN: 2196-8977

  • Edition Number: 1

  • Number of Pages: XIII, 475

  • Topics: Cardiology, Internal Medicine, Interventional Radiology, Vascular Surgery

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