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  • © 2008

Clinical Bioinformatics

  • Step-by-step instructions that ensure successful results
  • Tricks of the trade and notes on troubleshooting and avoiding known pitfalls

Part of the book series: Methods in Molecular Medicine (MIMM, volume 141)

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Table of contents (19 protocols)

  1. Front Matter

    Pages i-xi
  2. In Silico Gene Discovery

    • Bing Yu
    Pages 1-22
  3. Utilizing HapMap and Tagging SNPs

    • Christopher A. Haiman, Daniel O. Stram
    Pages 37-54
  4. Microarrays—Planning Your Experiment

    • Jean Yee Hwa Yang
    Pages 71-85
  5. Clinical Uses of Microarrays in Cancer Research

    • Carl Virtanen, James Woodgett
    Pages 87-113
  6. Microarrays—Analysis of Signaling Pathways

    • Anassuya Ramachandran, Michael A. Black, Andrew N. Shelling, Donald R. Love
    Pages 115-130
  7. Computer-Assisted Reading of DNA Sequences

    • Huong Le, Marcus Hinchcliffe, Bing Yu, Ronald J. A. Trent
    Pages 177-197
  8. Evaluating DNA Sequence Variants of Unknown Biological Significance

    • Scott A. Grist, Andrew Dubowsky, Graeme Suthers
    Pages 199-217
  9. Developing a DNA Variant Database

    • David C.Y. Fung
    Pages 219-243
  10. Protein Comparative Sequence Analysis and Computer Modeling

    • Brett D. Hambly, Cecily E. Oakley, Piotr G. Fajer
    Pages 245-256
  11. Statistical Analysis of Image Data Provided by Two-Dimensional Gel Electrophoresis for Discovery Proteomics

    • Ben Crossett, Alistair V. G. Edwards, Melanie Y. White, Stuart J. Cordwell
    Pages 271-286
  12. Online Resources for the Molecular Contextualization of Disease

    • Chi N.I. Pang, Marc R. Wilkins
    Pages 287-308
  13. Web-Based Resources for Clinical Bioinformatics

    • Anthony M. Joshua, Paul C. Boutros
    Pages 309-329
  14. Developing Decision Support Systems in Clinical Bioinformatics

    • Vitali Sintchenko, Enrico Coiera
    Pages 331-351
  15. eConsulting

    • Siaw-Teng Liaw, Peter Schattner
    Pages 353-373

About this book

With the ever-increasing volume of information in clinical medicine, researchers and health professionals need computer-based storage, processing and dissemination.  In Clinical Bioinformatics, leading experts in the field provide a series of articles focusing on software applications used to translate information into outcomes of clinical relevance. Covering such topics as gene discovery, gene function (microarrays), DNA mutation analysis, proteomics, online approaches and resources, and informatics in clinical practice, this volume concisely yet thoroughly explores its cutting edge subject. 

In this emerging "omics" era, Clinical Bioinformatics is the perfect guide for researchers and clinical scientists to unlock the complex, dense, and ever-growing accumulation of medical information.

Editors and Affiliations

  • Department of Molecular and Clinical Genetics, University of Sydney Central Clinical School Royal Prince Alfred Hospital, Camperdown, Australia

    Ronald J.A. Trent

Bibliographic Information

  • Book Title: Clinical Bioinformatics

  • Editors: Ronald J.A. Trent

  • Series Title: Methods in Molecular Medicine

  • DOI: https://doi.org/10.1007/978-1-60327-148-6

  • Publisher: Humana Totowa, NJ

  • eBook Packages: Springer Protocols

  • Copyright Information: Humana Press 2008

  • Hardcover ISBN: 978-1-58829-791-4Published: 18 December 2007

  • Softcover ISBN: 978-1-61737-781-5Published: 19 November 2010

  • eBook ISBN: 978-1-60327-148-6Published: 07 February 2008

  • Series ISSN: 1543-1894

  • Series E-ISSN: 1940-6037

  • Edition Number: 1

  • Number of Pages: XI, 382

  • Number of Illustrations: 89 b/w illustrations

  • Topics: Biochemistry, general, Bioinformatics, Cell Biology, Molecular Medicine, Proteomics, Human Genetics

Buy it now

Buying options

eBook USD 84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 109.00
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 109.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access