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Prostate Cancer

Signaling Networks, Genetics, and New Treatment Strategies

  • Book
  • © 2008

Overview

Editors:
  1. Richard G. Pestell

    1. Department of Cancer Biology Kimmel Cancer Center, Thomas Jefferson University, Philadelphia

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  2. Marja T. Nevalainen

    1. Department of Cancer Biology Kimmel Cancer Center, Thomas Jefferson University, Philadelphia

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    You can also search for this editor in PubMed   Google Scholar

  3. Michael Milken

    1. Prostate Cancer Foundation, Santa Monica

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    You can also search for this editor in PubMed   Google Scholar

  • Comprehensive, with up-to-date reviews on all aspects of biology and treatment of prostate cancer
  • Translational resource for clinicians and researchers
  • Discusses recent advances in prostate cancer treatment
  • Provides insight into future, novel treatment strategies

Part of the book series: Current Clinical Oncology (CCO)

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Table of contents (20 chapters)

  1. Front Matter

    Pages I-XV
    Download chapter PDF

  2. Histopathology and Molecular Biology of Prostate Atrophy

    • Alexander Valdman, Robert B. Jenkins, Fusheng Lan, Angelo M. De Marzo
    Pages 1-15

  3. Epigenetic Gene Silencing in Prostate Cancer

    • Srinivasan Yegnasubramanian, William G. Nelson
    Pages 17-52

  4. Inherited Genetic Changes in Prostate Cancer

    • John D. Carpten, Jeffrey M. Trent
    Pages 53-70

  5. Prostate Molecular Oncogenesis

    • Edward P. Gelmann
    Pages 71-97

  6. Somatic Genetic Changes in Prostate Cancer

    • Merja A. Helenius, Kati K. Waltering, Tapio Visakorpi
    Pages 99-128

  7. Androgen Receptor in Prostate Cancer Progression

    • Hiroshi Miyamoto, Saleh Altuwaijri, Chawnshang Chang
    Pages 129-146

  8. Epigenetic Modification and Acetylation of Androgen Receptor Regulate Prostate Cellular Growth

    • Michael J. Powell, Shengwen Li, Michael P. Lisanti, Marja T. Nevalainen, Chenguang Wang, Richard G. Pestell
    Pages 147-161

  9. Estrogen Receptor α and β in the Regulation of Normal and Malignant Prostate Epithelium

    • Otabek Imamov, Nikolai A. Lopatkin, Jan-Åke Gustafsson
    Pages 163-180

  10. Estrogen Action in Normal Prostate Epithelium and in Prostate Cancer

    • Gail S. Prins, Kenneth S. Korach
    Pages 181-207

  11. Hypoxia-Inducible Factor 1 in the Angiogenesis of Prostate Cancer

    • Jonathan W. Simons
    Pages 209-221

  12. Signal Transduction by the Ras–MAP Kinase Pathway in Prostate Cancer Progression

    • Daniel Gioeli, Sarah Kraus, Michael J. Weber
    Pages 223-256

  13. Transcription Factors STAT5 and STAT3

    • Zoran Culig, Richard G. Pestell, Marja T. Nevalainen
    Pages 257-290

  14. Role of PI3K–Akt and PTEN in the Growth and Progression of Prostate Cancer

    • Haojie Huang, Donald J. Tindall
    Pages 291-308

  15. New Perspectives in Prediction of Clinical Outcome of Prostate Cancer

    • Mark A. Rubin
    Pages 309-321

  16. New Directions in Radiation Therapy of Prostate Cancer

    • Sean Collins, Donald McRae, Gregory Gagnon, Anatoly Dritschilo
    Pages 323-338

  17. The Current Knowledge of Hormonal Therapy in the Treatment of Prostate Cancer

    • Mario A. Eisenberger
    Pages 339-354

  18. Advances in Surgical Intervention of Prostate Cancer

    • Jay B. Basillote, Thomas E. Ahlering, Douglas W. Skarecky
    Pages 355-382

  19. Targeted Therapy Trials for Prostate Cancer

    • Elisabeth I. Heath, Michael A. Carducci
    Pages 383-400

  20. New Perspectives on Chemotherapy in Prostate Cancer

    • Julia H. Hayes, Philip Kantoff
    Pages 401-425
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Keywords

About this book

Award winning authors present a comprehensive review of new perspectives in prostate cancer research and open up new directions in the clinical management of prostate cancer. In, “Prostate Cancer: Signaling Networks, Genetics, and New Treatment Strategies”, the authors focus on the biology, genetics, molecular signaling networks in the disease process, and recent advances in the treatment of prostate cancer. This state-of-the-art title provides key insights into cutting edge advances in prostate cancer research, such as laparoscopic radical prostatectomy, and offers a critical evaluation and discussion of opportunities for development of novel therapies for prostate cancer. Clinical trials that have not been covered or evaluated in any other books currently available are also discussed. Invaluable to physicians and researchers, “Prostate Cancer: Signaling Networks, Genetics, and New Treatment Strategies” provides a comprehensive translational resource as well as an important source of information for prostate cancer patients.

Reviews

From the reviews:

"In this detailed and up-to-date book, leaders in prostate cancer research review the current knowledge of genetic pathways and major molecular aberrations involved in prostate cancer as well as the treatment of the disease. … The figures and tables are clear and provide essential additional information. … the editors and authors have succeeded in clearly summarizing the most important recent advances in prostate cancer research, and the book will interest urologists, medical oncologists, and prostate cancer researchers." (Joost L. Boormans, The New England Journal of Medicine, August, 2008)

Editors and Affiliations

  • Department of Cancer Biology Kimmel Cancer Center, Thomas Jefferson University, Philadelphia

    Richard G. Pestell, Marja T. Nevalainen

  • Prostate Cancer Foundation, Santa Monica

    Michael Milken

Bibliographic Information

  • Book Title: Prostate Cancer

  • Book Subtitle: Signaling Networks, Genetics, and New Treatment Strategies

  • Editors: Richard G. Pestell, Marja T. Nevalainen, Michael Milken

  • Series Title: Current Clinical Oncology

  • DOI: https://doi.org/10.1007/978-1-60327-079-3

  • Publisher: Humana Totowa, NJ

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Humana Press 2008

  • Hardcover ISBN: 978-1-58829-741-9Published: 19 March 2008

  • Softcover ISBN: 978-1-60327-518-7Due: 06 May 2008

  • eBook ISBN: 978-1-60327-079-3Published: 26 February 2008

  • Series ISSN: 2364-1134

  • Series E-ISSN: 2364-1142

  • Edition Number: 1

  • Number of Pages: XVI, 456

  • Number of Illustrations: 22 b/w illustrations, 11 illustrations in colour

  • Topics: Urology, Oncology, Internal Medicine

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