Uterine Cancer

1. Front Matter

   Pages i-xi

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2. The Essential Epidemiology of Cancer of the Endometrium

   • Celeste L. Pearce, Karine Chung, Anna H. Wu, Malcolm C. Pike

   Pages 1-12

3. Endometrial Cancer

   • Annekathryn Goodman, Barbara Goff

   Pages 13-24

4. Imaging in the Diagnosis and Treatment of Endometrial Cancer

   • Mansi A. Saksena, Susanna I. Lee

   Pages 25-50

5. Uterine Cancer

   • Robert A. Soslow, Esther Oliva

   Pages 51-86

6. Molecular Pathology and Cytogenetics of Endometrial Carcinoma, Carcinosarcoma, and Uterine Sarcomas

   • Jose Palacios, Paola Dal Cin

   Pages 87-104

7. Prognostic Factors in Uterine Cancer

   • Patricia M. Baker, Esther Oliva

   Pages 105-141

8. Primary Hormonal Therapy of Endometrial Cancer

   • Linda R. Duska

   Pages 143-160

9. Early-Stage Endometrial Cancer

   • Yukio Sonoda

   Pages 161-173

10. Early-Stage Endometrial Cancer

    • Lea Baer, A. Gabriella Wernicke, Silvia Formenti

    Pages 175-192

11. Therapeutic Modalities in Early-Stage Uterine Papillary Serous Carcinomas, Carcinosarcomas, Clear-Cell and Mixed Histology Carcinomas

    • Nicholas P. Taylor, Matthew A. Powell

    Pages 193-216

12. Treatment of Advanced and Recurrent Carcinoma

    • Franco Muggia, Stephanie V. Blank

    Pages 217-222

13. Treatment of Advanced and Recurrent Carcinoma: Chemotherapy

    • Halla Nimeiri, Gini F. Fleming

    Pages 223-235

14. Treatment for Advanced and Recurrent Carcinoma: Combined Modalities

    • Marcela G. del Carmen, Neil S. Horowitz

    Pages 237-249

15. Management of Uterine Sarcomas

    • Carolyn Krasner, Martee L. Hensley

    Pages 251-265

16. Future Directions: New Targets

    • Franco Muggia, Leslie I. Gold, John Curtin

    Pages 267-283

17. Back Matter

    Pages 285-296

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For the Editors, the task of writing a Preface is most satisfying. It represents the completion of the book and a moment of reflection on whether the whole is more than the sum of all the parts. And also, one must reflect on how this book is likely to be utilized in this era of rapid communications. The Editors first met in May 2003 at a stimulating Italian symposium on endometrial cancer (organizers Drs. Luigi Frigerio, Roberto Grassi and Andrea Lissoni, with participation of the deans of Italian Gynecologic Oncology, Ugo Bianchi and Constantino Mangioni) that took place at Bergamo and Caravaggio. The impressive gains in biology and clinical trials were further discussed by the two editors and others that are co-authors in this venture on this side of the Atlantic at a 2004 Educational Session at the American Society of Clinical Oncology (ASCO). The pace of progress in various aspects of management of uterine cancer was no- worthy, not only was tumor biology fueling novel hypotheses such as questioning the mesenchymal origin of carcinosarcomas, but knowledge of molecular pathways was beginning to be applied as prognostic and as predictive factors portending benefit from systemic therapies. Surgical staging and sensitive imaging provided the underpinning for refining our treatment algorithms. Finally, a role for che- therapy had finally become established, principally through phase III studies c- paring chemotherapy to radiation in mostly locally advanced stages III and IV that had undergone resection.

• Cancer
• Carcinom
• Chemotherapy
• Endometrial Cancer
• Epidemiology
• Staging
• Uterine Sarcomas
• surgery

From the reviews: “This short monograph comprises 15 chapters written by 31 contributors and covers the epidemiology, pathology, staging, and management of uterine cancers. … This book provides some useful background on endometrial cancer and … helpful for a radiation oncologist with a special interest in gynecologic cancers. … directed primarily at an audience of gynecologic oncologists … .” (David S. Shimm, International Journal of Radiation - Oncology - Biology - Physics, Vol. 77 (2), 2010)

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