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Biological Microarrays

Methods and Protocols

  • Book
  • © 2011

Overview

Editors:
  1. Ali Khademhosseini

    1. , MIT Division of Health Sciences and Tech, Harvard Medical School, Cambridge, USA

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    You can also search for this editor in PubMed   Google Scholar

  2. Kahp-Yang Suh

    1. , Department of Mechanical and Aerospace E, Seoul National University, Seoul, Korea, Republic of (South Korea)

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  3. Mohammed Zourob

    1. Biophage Pharma, Inc., Montreal, Canada

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  • Comprehensive presentation of various biological microarrays and their applications
  • Includes methods for analysis and characterization of the resulting arrays
  • Provides description of synthesis methods and areas of use
  • Includes supplementary material: sn.pub/extras

Part of the book series: Methods in Molecular Biology (MIMB, volume 671)

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Table of contents (18 protocols)

  1. Front Matter

    Pages i-xi
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  2. Application of Biological Microarray

    1. Front Matter

      Pages 1-1
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    2. RNA and DNA Microarrays

      • Stuart C. Sealfon, Tearina T. Chu
      Pages 3-34

    3. Aptamer Arrays

      • Eva Baldrich
      Pages 35-54

    4. Oligonucleotide Microarrays for Identification of Microbial Pathogens and Detection of Their Virulence-Associated or Drug-Resistance Determinants

      • Dmitriy V. Volokhov, Hyesuk Kong, Keith Herold, Vladimir E. Chizhikov, Avraham Rasooly
      Pages 55-94

    5. Protein Microarrays Printed from DNA Microarrays

      • Oda Stoevesandt, Mingyue He, Michael J. Taussig
      Pages 95-106

    6. Lithographically Defined Two- and Three-Dimensional Tissue Microarrays

      • Esther W. Gomez, Celeste M. Nelson
      Pages 107-116

    7. Ratiometric Lectin Microarray Analysis of the Mammalian Cell Surface Glycome

      • Ku-Lung Hsu, Kanoelani Pilobello, Lakshmipriya Krishnamoorthy, Lara K. Mahal
      Pages 117-131

    8. Cell Microarrays Based on Hydrogel Microstructures for the Application to Cell-Based Biosensor

      • Won-Gun Koh
      Pages 133-145

    9. Fabrication of Bacteria and Virus Microarrays Based on Polymeric Capillary Force Lithography

      • Pil J. Yoo
      Pages 147-160

    10. 3D Polymer Scaffold Arrays

      • Carl G. Simon Jr., Yanyin Yang, Shauna M. Dorsey, Murugan Ramalingam, Kaushik Chatterjee
      Pages 161-174

  3. Methods for Microarray Generation

    1. Front Matter

      Pages 175-175
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    2. PDMS Microfluidic Capillary Systems for Patterning Proteins on Surfaces and Performing Miniaturized Immunoassays

      • Mateu Pla-Roca, David Juncker
      Pages 177-194

    3. Merging Photolithography and Robotic Protein Printing to Create Cellular Microarrays

      • Ji Youn Lee, Alexander Revzin
      Pages 195-206

    4. Generation of Protein and Cell Microarrays on Functionalized Surfaces

      • Yoo Seong Choi, Chang-Soo Lee
      Pages 207-217

    5. Microprinting of Liver Micro-organ for Drug Metabolism Study

      • Robert C. Chang, Kamal Emami, Antony Jeevarajan, Honglu Wu, Wei Sun
      Pages 219-238

    6. Microcontact Printing

      • Yunyan Xie, Xingyu Jiang
      Pages 239-248

    7. Micromolding for the Fabrication of Biological Microarrays

      • Ashley L. Galloway, Andrew Murphy, Jason P. Rolland, Kevin P. Herlihy, Robby A. Petros, Mary E. Napier et al.
      Pages 249-260

    8. Progress Report on Microstructured Surfaces Based on Chemical Vapor Deposition

      • Yaseen Elkasabi, Joerg Lahann
      Pages 261-279

    9. Methods for Forming Human Microvascular Tubes In Vitro and Measuring Their Macromolecular Permeability

      • Gavrielle M. Price, Joe Tien
      Pages 281-293
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Keywords

About this book

Recent developments in microarray technology have changed the landscape of biology and biomedical research, and they have revolutionized RNA and DNA research. In Biological Microarrays: Methods and Protocols, expert researchers explore exciting new developments in the field, providing a comprehensive approach to biological microarrays that conveys not only the state-of-the-art fundamentals, but also includes applications of the most innovative methods. Chapters address both the application of biological microarrays, including DNA/RNA, apatmer, proteins, tissues, oligonucleotides, carbohydrates, biomaterials, cells, bacteria, and virus microarrays, and also explore the different techniques used for generating microarray platforms. Composed in the highly successful Methods in Molecular Biology™ series format, each chapter contains a brief introduction, step-by-step methods, a list of necessary materials, and a Notes section which shares tips on troubleshooting and avoiding known pitfalls. Wide-ranging and revolutionary, Biological Microarrays: Methods and Protocols serves as a primary source for academics, practitioners, and professionals in related fields, including biologists, biotechnologists, biochemists, analytical chemists, and biomedical, physical, and microsystems engineers, to name a few, appealing to all of those interested in the present and future state of biological microarray research.

Editors and Affiliations

  • , MIT Division of Health Sciences and Tech, Harvard Medical School, Cambridge, USA

    Ali Khademhosseini

  • , Department of Mechanical and Aerospace E, Seoul National University, Seoul, Korea, Republic of (South Korea)

    Kahp-Yang Suh

  • Biophage Pharma, Inc., Montreal, Canada

    Mohammed Zourob

Bibliographic Information

  • Book Title: Biological Microarrays

  • Book Subtitle: Methods and Protocols

  • Editors: Ali Khademhosseini, Kahp-Yang Suh, Mohammed Zourob

  • Series Title: Methods in Molecular Biology

  • DOI: https://doi.org/10.1007/978-1-59745-551-0

  • Publisher: Humana Totowa, NJ

  • eBook Packages: Springer Protocols

  • Copyright Information: Springer Science + Business Media, LLC 2011

  • Hardcover ISBN: 978-1-934115-95-4Published: 28 October 2010

  • Softcover ISBN: 978-1-4939-5763-7Published: 23 August 2016

  • eBook ISBN: 978-1-59745-551-0Published: 22 October 2010

  • Series ISSN: 1064-3745

  • Series E-ISSN: 1940-6029

  • Edition Number: 1

  • Number of Pages: XI, 324

  • Topics: Biotechnology, Human Genetics

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