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  • © 2008

Oxidative Stress in Aging

From Model Systems to Human Diseases

  • State-of-the-art overview of the free radical theory of aging and oxidative biochemistry
  • Evaluates the role of oxidative stress in the aging process in different model organisms
  • Discusses connection between free radicals, various diseases, and age-related pathological conditions
  • Reviews major interventions trials of antioxidant supplements in age-related diseases
  • Includes supplementary material: sn.pub/extras

Part of the book series: Aging Medicine (AGME)

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Table of contents (17 chapters)

  1. Front Matter

    Pages i-xiii
  2. Introduction

    1. Introduction

      • Satomi Miwa, Florian L. Muller, Kenneth B. Beckman
      Pages 3-10
    2. The Basics of Oxidative Biochemistry

      • Satomi Miwa, Florian L. Muller, Kenneth B. Beckman
      Pages 11-35
  3. The Role of Oxidative Stress in Aging

    1. The Comparative Approach

  4. Oxidative Stress in Human Aging and Diseases

    1. Oxidative Stress in Type 2 Diabetes Mellitus

      • Muhammad A. Abdul-Ghani, Ralph A. DeFronzo
      Pages 191-211
    2. DNA Oxidative Damage and Cancer

      • Jeffrey A. Stuart, Melissa M. Page
      Pages 213-228
    3. Oxidative Stress in Hypertension

      • Sean P. Didion, Sophocles Chrissobolis, Frank M. Faraci
      Pages 229-251
  5. Future

    1. Reactive Oxygen Species as Signaling Molecules

      • Ilsa I. Rovira, Toren Finkel
      Pages 293-307
    2. Summary and Outlook

      • Satomi Miwa, Florian L. Muller, Kenneth B. Beckman
      Pages 309-312
  6. Back Matter

    Pages 313-320

About this book

Oxidative Stress in Aging: From Model Systems to Human Diseases discusses the role of free radicals in aging in different animal models, as well as the relevance of free radicals on age-related diseases and pathological conditions in humans (following an introduction section of the basics and theory of free radicals). Human aging is a complex phenomenon - not everyone gets the same diseases and dies from the same cause. Accumulating reports implicate the connection between free radicals and various diseases and age-related pathological conditions. Although the causal relationships have not been established, it is necessary to discuss how free radicals are involved in each situation. In addition, the major interventions trials of antioxidant supplements in age-related disease, cancer and so forth are reviewed and discussed.

Editors and Affiliations

  • Institute for Ageing and Health, Newcastle University, Newcastle upon Tyne, UK

    Satomi Miwa

  • Functional Genomics Core, Children's Hospital Oakland Research Institute, Oakland, USA

    Kenneth B. Beckman

  • Department of Cellular and Structural Biology, University of Texas Health Science Center at San Antonio, San Antonio, USA

    Florian L. Muller

Bibliographic Information

  • Book Title: Oxidative Stress in Aging

  • Book Subtitle: From Model Systems to Human Diseases

  • Editors: Satomi Miwa, Kenneth B. Beckman, Florian L. Muller

  • Series Title: Aging Medicine

  • DOI: https://doi.org/10.1007/978-1-59745-420-9

  • Publisher: Humana Totowa, NJ

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Humana Press 2008

  • Hardcover ISBN: 978-1-58829-991-8Published: 30 May 2008

  • Softcover ISBN: 978-1-61737-870-6Published: 10 December 2010

  • eBook ISBN: 978-1-59745-420-9Published: 17 June 2008

  • Edition Number: 1

  • Number of Pages: VIII, 320

  • Number of Illustrations: 27 b/w illustrations, 1 illustrations in colour

  • Topics: Geriatrics/Gerontology, Internal Medicine, Cell Biology

Buy it now

Buying options

eBook USD 89.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 119.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access