Overview
- Readily reproducible, cutting-edge techniques for studying the biology of apoptosis
- Step-by-step instructions that ensure successful results
- Tricks of the trade and notes on troubleshooting and avoiding known pitfalls
Part of the book series: Methods in Molecular Biology (MIMB, volume 414)
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Table of contents (17 protocols)
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Front Matter
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Back Matter
Keywords
About this book
Our understanding of the apoptotic pathway and its regulation has improved significantly in the last 10 years. However, as our knowledge of the intricate intracellular events increase, we realize the complexity of the regulatory mechanisms that control it. As such, Apoptosis and Cancer describes the performance of contemporary techniques for studying the biology of apoptosis and its role in cancer. This book is a collaboration between academics- and industry-based scientists. The chapters have the technical development characteristic of an academic environment and the standardized system necessary for translating a product to general use, as provided by the industry. Thus, the protocols described within this groundbreaking new volume will aid both an academic laboratory interested in further characterizing the mechanism of apoptosis and an industry laboratory interested on identifying new target molecules or screening for new compounds with potential clinical use. The authors – all leaders in the field – have created a comprehensive text that covers the newest available techniques as well as conventional basic techniques. Apoptosis and Cancer will undoubtedly provide the necessary resources to everyone interested in the area of apoptosis.
Reviews
From the reviews:
"Divided among 17 chapters, the condensed information about apoptosis, its pathways and the performance of progressive techniques for apoptosis assessment are presented. … The valuable and most appreciated part of each chapter are notes – the reader will find here the plethora of hints, the real grain of wisdom, virtual wizard that saves a lot of struggling time at benchtop. This book belongs to the category of must-have books." (J. Sedlák, Neoplasma, September, 2008)
Editors and Affiliations
Bibliographic Information
Book Title: Apoptosis and Cancer
Book Subtitle: Methods and Protocols
Editors: Gil Mor, Ayesha B. Alvero
Series Title: Methods in Molecular Biology
DOI: https://doi.org/10.1007/978-1-59745-339-4
Publisher: Humana Totowa, NJ
eBook Packages: Springer Protocols
Copyright Information: Humana Press 2008
Hardcover ISBN: 978-1-58829-457-9Published: 11 October 2007
Softcover ISBN: 978-1-61737-582-8Published: 19 November 2010
eBook ISBN: 978-1-59745-339-4Published: 03 February 2008
Series ISSN: 1064-3745
Series E-ISSN: 1940-6029
Edition Number: 1
Number of Pages: XI, 266
Number of Illustrations: 69 b/w illustrations
Topics: Oncology, Cancer Research, Cell Biology, Molecular Medicine, Biochemistry, general