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Renal Cell Carcinoma

Molecular Targets and Clinical Applications, Second Edition

  • Book
  • © 2009

Overview

  • Explores the development and use of angiogenesis and tyrosine kinase inhibitors in epithelial renal tumor treatment
  • Presents the latest findings in the field of molecular medicine and the exploration of novel targets as therapies for renal cell carcinomas
  • Provides substantive background on the research data and clinical findings of the latest gene therapy studies
  • Includes supplementary material: sn.pub/extras

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Table of contents (25 chapters)

Keywords

About this book

In the second edition of their critically acclaimed book, Ronald Bukowski, Robert Motzer, and Robert Figlin have thoroughly updated and expanded their survey of clinical, biological and pathological management of localized and advanced renal cell carcinoma. A panel of internationally renowned contributors explores the latest developments in molecular genetics, focusing on the novel targets that have been discovered in epithelial renal tumors. The discussion includes the specific biology of selected target molecules or receptors and the various agents that inhibit these targets, including full chapters devoted to drugs that selectively inhibit receptor tyrosine kinases, such as sunitinib and axitinib. Further attention is paid to leading-edge strategies that target and inhibit tumor associated angiogenesis and block the vascular endothelial growth factor pathway. Comprehensive and authoritative, Renal Cell Carcinoma: Molecular Targets and Clinical Applications, Second Edition is the definitive text on the rapidly evolving landscape of experimental therapeutics, written and edited by the pioneers of the field.

Reviews

From the reviews of the second edition:

"Chapters in this book are written by an authoritative group of contributors who are well known for their translational and clinical work in kidney cancer. … The primary audience includes individuals on the cusp of translational … in kidney cancer. … for most practicing medical oncologists, the book provides essential data upon which their daily clinical decisions are based when caring for patients afflicted with kidney cancer. … The strength of this book lies in … its sharp insights into a rapidly evolving field." (Robert G Uzzo, Doody’s Review Service, June, 2009)

Editors and Affiliations

  • Cleveland Clinic Foundation, Cleveland Clinic Taussig Cancer Center and CCF Lerner College of Medicine of CWRU, Cleveland

    Ronald M. Bukowski

  • Division of Medical Oncology & Experimental Therapeutics, City of Hope National Medical, Center/Beckman Research Institute, Duarte

    Robert A. Figlin

  • Memorial-Sloan Kettering Cancer Center, New York

    Robert J. Motzer

Bibliographic Information

  • Book Title: Renal Cell Carcinoma

  • Book Subtitle: Molecular Targets and Clinical Applications, Second Edition

  • Editors: Ronald M. Bukowski, Robert A. Figlin, Robert J. Motzer

  • DOI: https://doi.org/10.1007/978-1-59745-332-5

  • Publisher: Humana Totowa, NJ

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Humana Press 2009

  • Softcover ISBN: 978-1-60761-468-5Due: 17 March 2010

  • eBook ISBN: 978-1-59745-332-5Published: 08 February 2009

  • Edition Number: 2

  • Number of Pages: XVIII, 506

  • Number of Illustrations: 25 illustrations in colour

  • Topics: Oncology, Nuclear Medicine

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