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Cell Therapy, Stem Cells and Brain Repair

  • Book
  • © 2007

Overview

Editors:
  1. Cyndy Davis Sanberg

    1. Saneron CCEL Therapeutics, Tampa

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    You can also search for this editor in PubMed   Google Scholar

  2. Paul R. Sanberg

    1. University of South Florida College of Medicine, Tampa

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

Part of the book series: Contemporary Neuroscience (CNEURO)

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Table of contents (14 chapters)

  1. Front Matter

    Pages i-xvi
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  2. Current Views of the Embryonic and Neural Stem Cell

    • Roya Sabetrasekh, Yang D. Teng, Jitka Ourednik, Kook In Park, Evan Y. Snyder
    Pages 1-30

  3. Developing Novel Cell Sources for Transplantation in Parkinson’s Disease

    • Nicolaj S. Christophersen, Ana Sofia Correia, Laurent Roybon, Jia-Yi Li, Patrik Brundin
    Pages 31-60

  4. Neural Transplantation in the Nonhuman Primate Model of Parkinson’s Disease

    • Kimberly B. Bjugstad, John R. Sladek Jr.
    Pages 61-82

  5. Cell-Based Therapy for Huntington’s Disease

    • Claire M. Kelly, Stephen B. Dunnett, Anne E. Rosser
    Pages 83-116

  6. Use of Bone Marrow Stem Cells as Therapy for Behavioral Deficits in Rodent Models of Huntington’s Disease

    • Gary L. Dunbar, Justin D. Oh-Lee, Laurent Lescaudron
    Pages 117-138

  7. Human Neuroteratocarcinoma Cells as a Neural Progenitor Graft Source for Cell Transplantation in Stroke

    • Cesario V. Borlongan, Christina Fournier, David C. Hess, Paul R. Sanberg
    Pages 139-162

  8. Therapeutic Applications of Bone Marrow-Derived Stem Cells in Neurologic Injury and Disease

    • C.Dirk Keene, Xilma R. Ortiz-Gonzalez, Yuehua Jiang, Catherine M. Verfaillie, Walter C. Low
    Pages 163-197

  9. Cell Therapy for Models of Pain and Traumatic Brain Injury

    • Mary Eaton, Jacqueline Sagen
    Pages 199-239

  10. The Use of Sertoli Cells in Neural Transplantation

    • Dwaine F. Emerich, Cesario V. Borlongan, Craig R. Halberstadt
    Pages 241-259

  11. The Choroid Plexus

    • Cesario V. Borlongan, Stephen J. M. Skinner, Alfred Vasconcellos, Robert B. Elliott, Dwaine F. Emerich
    Pages 261-285

  12. Progress and Challenges in Immunoisolation for CNS Cell Therapy

    • Christopher G. Thanos, Dwaine F. Emerich
    Pages 287-323

  13. Evidence-Based Methodology for Advancing Neural Reconstruction

    • Stephen Polgar
    Pages 325-339

  14. Hematopoietic Cell Therapy for Brain Repair

    • Martina Vendrame, Alison E. Willing
    Pages 341-362

  15. Stem Cells and Regenerative Medicine

    • L. Eduardo Cruz, Silvia P. Azevedo
    Pages 363-383

  16. Back Matter

    Pages 385-391
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Keywords

About this book

As our world continues to evolve, the field of regenerative medicine f- lows suit. Although many modern day therapies focus on synthetic and na- ral medicinal treatments for brain repair, many of these treatments and prescriptions lack adequate results or only have the ability to slow the p- gression of neurological disease or injury. Cell therapy, however, remains the most compelling treatment for neurodegenerative diseases, disorders, and injuries, including Parkinson’s disease, Huntington’s disease, traumatic brain injury, and stroke, which is expanded upon in more detail in Chapter 1 by Snyder and colleagues. Cell therapy is also unique in that it is the only therapeutic strategy that strives to replace lost, damaged, or dysfunctional cells with healthy ones. This repair and replacement may be due to an administration of exogenous cells itself or the activation of the body’s own endogenous reparative cells by a trophic, immune, or inflammatory response to cell transplantation. However, the precise mechanism of how cell therapy works remains elusive and is c- tinuing to be investigated in terms of molecular and cellular responses, in particular. Moreover, Chapter 11 by Emerich and associates, discusses some of the possibilities of cell immunoisolation and the potential for treating central nervous system diseases.

Reviews

"...covers the wide field of cell therapy and evaluates potential future treatments for neurodegenerative diseases and brain injuries...suitable for scientists and clinicians to gain a comprehensive overview on modern stem-cell research in regenerative medicine." -Schwfizer Archiv fur Neruologie und Psychiatrie

Editors and Affiliations

  • Saneron CCEL Therapeutics, Tampa

    Cyndy Davis Sanberg

  • University of South Florida College of Medicine, Tampa

    Paul R. Sanberg

Bibliographic Information

  • Book Title: Cell Therapy, Stem Cells and Brain Repair

  • Editors: Cyndy Davis Sanberg, Paul R. Sanberg

  • Series Title: Contemporary Neuroscience

  • DOI: https://doi.org/10.1007/978-1-59745-147-5

  • Publisher: Humana Totowa, NJ

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Humana Press 2007

  • Hardcover ISBN: 978-1-58829-502-6Published: 01 September 2006

  • Softcover ISBN: 978-1-61737-604-7Published: 09 December 2010

  • eBook ISBN: 978-1-59745-147-5Published: 09 November 2007

  • Edition Number: 1

  • Number of Pages: XVI, 392

  • Number of Illustrations: 45 b/w illustrations, 1 illustrations in colour

  • Topics: Neurosciences

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