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Transplantation Immunology

Methods and Protocols

  • Book
  • © 2006

Overview

Editors:
  1. Philip Hornick

    1. National Heart and Lung Institute, London, UK

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    You can also search for this editor in PubMed   Google Scholar

  2. Marlene Rose

    1. National Heart and Lung Institute, Harefield, UK

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

Part of the book series: Methods in Molecular Biology (MIMB, volume 333)

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Table of contents (17 protocols)

  1. Front Matter

    Pages i-x
    Download chapter PDF

  2. Current Status of Renal Transplantation

    • Christopher J. Callaghan, J. Andrew Bradley
    Pages 1-27

  3. Current Status of Liver Transplantation

    • Peter J. Friend, Charles J. Imber
    Pages 29-46

  4. Current Status of Clinical Islet Cell Transplantation

    • Jonathan R. T. Lakey, Mohammadreza Mirbolooki, A. M. James Shapiro
    Pages 47-103

  5. Current Status of Lung Transplantation

    • Allan R. Glanville
    Pages 105-130

  6. Chronic Rejection in the Heart

    • Philip Hornick, Marlene Rose
    Pages 131-144

  7. Direct and Indirect Allorecognition

    • Philip Hornick
    Pages 145-156

  8. HLA Typing and Its Influence on Organ Transplantation

    • Stephen Sheldon, Kay Poulton
    Pages 157-174

  9. Strategies for Gene Transfer to Solid Organs

    • Charlotte Lawson
    Pages 175-199

  10. Nonviral Vectors

    • Louise Collins
    Pages 201-225

  11. Detection and Clinical Relevance of Antibodies After Transplantation

    • John D. Smith, Marlene Rose
    Pages 227-245

  12. 11 Reprogramming the Immune System Using Antibodies

    • Luis Graca, Herman Waldmann
    Pages 247-267

  13. In Vitro Assays for Immune Monitoring in Transplantation

    • Maria P. Hernandez-Fuentes, Alan Salama
    Pages 269-290

  14. Proteomics and Laser Microdissection

    • Emma McGregor, Ayesha De Souza
    Pages 291-304

  15. Real-Time Quantitative Polymerase Chain Reaction in Cardiac Transplant Research

    • Leanne E. Felkin, Anne B. Taegtmeyer, Paul J. R. Barton
    Pages 305-330

  16. Organ Preservation

    • Mark Hicks, Alfred Hing, Ling Gao, Jonathon Ryan, Peter S. MacDonald
    Pages 331-373

  17. Pharmacological Manipulation of the Rejection Response

    • Peter Mark Anthony Hopkins
    Pages 375-399

  18. Experimental Models of Graft Arteriosclerosis

    • Bezhad Soleimani, Victor C. Shi
    Pages 401-423

  19. Back Matter

    Pages 425-429
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Keywords

About this book

Leading clinicians and scientists in solid organ transplantation review the current status of the field and describe cutting-edge techniques for detecting the immune response to the allografted organ. The authors present the latest techniques for HLA typing, detecting HLA antibodies, and monitoring T-cell response, and examine more specialized methods utilizing proteomics, laser dissection microscopy, and real-time polymerase chain reaction. The area of tolerance induction and reprogramming of the immune system is also covered, along with a discussion of up-to-date methods of organ preservation, of today's optimal immunosuppressive drug regimens, as well as the difficulty of mimicking chronic rejection in experimental models. Introductory chapters provide a theoretical update on current practices in renal, liver, islet, and lung transplantation and on the pathways of antigen presentation and chronic rejection.

Editors and Affiliations

  • National Heart and Lung Institute, London, UK

    Philip Hornick

  • National Heart and Lung Institute, Harefield, UK

    Marlene Rose

Bibliographic Information

  • Book Title: Transplantation Immunology

  • Book Subtitle: Methods and Protocols

  • Editors: Philip Hornick, Marlene Rose

  • Series Title: Methods in Molecular Biology

  • DOI: https://doi.org/10.1385/1597450499

  • Publisher: Humana Totowa, NJ

  • eBook Packages: Springer Protocols

  • Copyright Information: Humana Press 2006

  • Hardcover ISBN: 978-1-58829-544-6Published: 01 March 2006

  • Softcover ISBN: 978-1-61737-632-0Published: 01 December 2010

  • eBook ISBN: 978-1-59745-049-2Published: 05 February 2008

  • Series ISSN: 1064-3745

  • Series E-ISSN: 1940-6029

  • Edition Number: 1

  • Number of Pages: X, 430

  • Number of Illustrations: 54 b/w illustrations

  • Topics: Immunology

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