Squamous Cell Head and Neck Cancer

1. Front Matter

   Pages i-x

   PDF

2. Head and Neck Squamous Cell Cancers in the Nonsmoker-Nondrinker

   • Gypsyamber D’Souza, Maura L. Gillison

   Pages 1-26

3. Laryngeal Preservation Surgery

   • Joseph Scharpf, Robert R. Lorenz

   Pages 27-42

4. Laser Surgery for Head and Neck Cancer

   • Lee M. Akst, Marshall Strome

   Pages 43-57

5. The Evolving Role of Neck Dissection in the Era of Organ Preservation Therapy for Head and Neck Squamous Cell Carcinoma

   • Tung T. Trang, Pierre Lavertu

   Pages 59-68

6. Salvage Surgery After Chemoradiation Therapy

   • Walter T. Lee, Ramon M. Esclamado

   Pages 69-78

7. T3–T4 Squamous Cell Carcinoma of the Larynx Treated With Radiation Therapy Alone or Combined With Adjuvant Chemotherapy

   • William M. Mendenhall

   Pages 79-92

8. Role of Brachytherapy in Treatment of Head and Neck Malignancy

   • Ravi A. Shankar, Kenneth S. Hu, Louis B. Harrison

   Pages 93-113

9. Intensity-Modulated Radiation Therapy in the Management of Head and Neck Cancer

   • Theodore S. Hong, Wolfgang A. Tomé, Paul M. Harari

   Pages 115-124

10. Altered Fractionation

    • Anesa Ahamad, David I. Rosenthal, K. Kian Ang

    Pages 125-144

11. The Role of Tumor Hypoxia in Head and Neck Cancer Radiotherapy

    • Quynh-Thu Le, Amato J. Giaccia, J. Martin Brown

    Pages 145-163

12. Induction Chemotherapy in Head and Neck Cancer

    • Danny Rischin

    Pages 165-170

13. The Evolution of Induction Chemotherapy in Locally Advanced Squamous Cell Cancer of the Head and Neck

    • Marshall R. Posner, Lori Wirth, Roy B. Tishler, Charles M. Norris, Robert I. Haddad

    Pages 171-185

14. Concurrent Chemoradiotherapy

    • David J. Adelstein

    Pages 187-195

15. Postoperative Treatment of Locally Advanced Head and Neck Cancers

    • Jacques Bernier, Søren M. Bentzen

    Pages 197-210

16. Multimodality Management of Nasopharyngeal Carcinoma

    • Eng-Huat Tan, Swan-Swan Leong, Terence Tan, Kam-Weng Fong, Joseph Wee

    Pages 211-225

17. Strategies for Protecting Normal Tissue in the Treatment of Head and Neck Cancer

    • David M. Brizel

    Pages 227-237

18. Targeted Therapies in Head and Neck Cancer

    • Tanguy Y. Seiwert, Ezra E. W. Cohen

    Pages 239-261

19. Gene Therapy for Patients With Head and Neck Cancer

    • Andrew Iskander, George H. Yoo

    Pages 263-278

20. Chemoprevention in Head and Neck Cancer

    • Nabil F. Saba, Fadlo R. Khuri

    Pages 279-303

Leading expert physicians and investigators from around the world review the state-of-the-art in the management of squamous cell head and neck cancer, with emphasis on coordinating different treatment modalities. The authors address several surgical issues, including laser-based surgery, larynx preservation approaches, salvage surgery, and neck management after non-operative treatment. They also discuss definitive radiation for larynx cancer, brachytherapy, altered fractionation radiation, intensity modulated radiation therapy, and the importance of tumor hypoxia, as well as the role of chemotherapy in sequential, concurrent, and adjuvant multi-modality treatment schedules. Other topics of special interest include targeted and gene therapies, multimodality management of nasopharyngeal cancer, chemoprevention, toxicity modification, quality of life outcomes, symptom palliation, and epidemiology.

• brachytherapy
• cancer
• carcinoma
• cell
• chemotherapy
• clinical trial
• dosimetry
• gene therapy
• laser
• magnetic resonance imaging (MRI)
• prevention
• radiation
• radiotherapy
• surgery
• tumor

"...will be a valuable tool for surgeonms and oncologists who deal with head and neck cancer.  It would also be a useful addition to any institution's library." - The New England Journal of Medicine

"...packed with data giving glimpses of the future." - Annals of the Royal College of Surgeons of England

• Department of Hematology and Medical Oncology, Cleveland Clinic Foundation, Cleveland

  David J. Adelstein

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