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Lymphoma

  • Book
  • © 2005

Overview

Editors:
  1. Tim Illidge

    1. CRUK, Paterson Institute for Cancer Research, University of Manchester, Manchester, UK

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    You can also search for this editor in PubMed   Google Scholar

  2. Peter W. M. Johnson

    1. Cancer Sciences Division, Southampton General Hospital, Southampton, UK

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

Part of the book series: Methods in Molecular Medicine (MIMM, volume 115)

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Table of contents (16 protocols)

  1. Front Matter

    Pages i-xiv
    Download chapter PDF

  2. Purification of Primary Malignant B-Cells and Immunoblot Analysis of Bcl-2 Family Proteins

    • Claire Dallman, Graham Packham
    Pages 1-13

  3. Molecular Diagnosis of Lymphoma

    • Kim Last, Silvana Debarnardi, T. Andrew Lister
    Pages 15-63

  4. Demonstration of a Germinal Center Immunophenotype in Lymphomas by Immunocytochemistry and Flow Cytometry

    • Andrew Jack, Sharon Barrans, David Blythe, Andrew Rawstron
    Pages 65-91

  5. Karyotyping Lymph Node Biopsies in Non-Hodgkin’s Lymphoma

    • Fiona M. Ross, Christine J. Harrison
    Pages 93-107

  6. Identification of Lymphoma-Associated Antigens Using SEREX

    • Amanda P. Liggins, Barbara A. Guinn, Alison H. Banham
    Pages 109-128

  7. Determining Mutational Status of Immunoglobulin V Genes in Chronic Lymphocytic Leukemia

    • Surinder S. Sahota, Gavin Babbage, Niklas Zojer, Christian H. Ottensmeier, Freda K. Stevenson
    Pages 129-144

  8. Idiotype Gene Rescue in Follicular Lymphoma

    • Katy McCann, Surinder S. Sahota, Freda K. Stevenson, Christian H.
    Pages 145-171

  9. Immunoglobulin Gene Mutation Patterns and Heterogeneity of Marginal Zone Lymphoma

    • Mariella Dono, Manlio Ferrarini
    Pages 173-196

  10. T-Cell Receptor Molecular Diagnosis of T-Cell Lymphoma

    • Elizabeth Hodges, Anthony P. Williams, Susan Harris, John L. Smith
    Pages 197-215

  11. Cloning of Immunoglobulin Chromosomal Translocations by Long-Distance Inverse Polymerase Chain Reaction

    • E. Loraine Karran, Takashi Sonoki, Martin J. S. Dyer
    Pages 217-230

  12. Sequential Fluorescence In Situ Hybridization Analysis for Trisomy 12 in B-Cell Chronic Lymphocytic Leukemia

    • Viktoria Hjalmar
    Pages 231-240

  13. Splenic Marginal Zone Lymphoma

    • Rachel E. Ibbotson, Anton E. Parker, David G. Oscier
    Pages 241-250

  14. BCL-6

    • Simon D. Wagner, Jaspal S. Kaeda
    Pages 251-269

  15. Antibody Techniques Used in the Study of Anaplastic Lymphoma Kinase-Positive ALCL

    • Karen Pulford, Helen M. Roberton, Margaret Jones
    Pages 271-294

  16. Identification of Anaplastic Lymphoma Kinase Variant Translocations Using 5′RACE

    • Luis Hernáandez, Elias Campo
    Pages 295-313

  17. Follicular Lymphoma

    • Angela Darby, John G. Gribben
    Pages 315-331

  18. Back Matter

    Pages 333-342
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Keywords

About this book

A cutting-edge collection of readily reproducible molecular techniques to better understand, classify, and treat lymphoma. Among the highlights are methods to use immunoglobulin gene rearrangements as markers of clonality, to exploit patterns of somatic mutation in the variable regions to indicate at which stage transformation occurred, and to apply gene arrays to the question of biological heterogeneity in morphologically similar diseases. Research methodologies that are highly likely to become routine practice in the future, such as DNA microarray and immunoglobulin V-gene rearrangements, and measurement of minimal disease, are included. There are also molecular techniques for providing for producing novel therapeutics, such as a DNA vaccine with patient-specific sequences derived from the lymphoma in question.

Reviews

"Offers(s) a diverse collection of readily reproducible techniques for the molecular diagnosis and prognostic evaluation of lymphomas..." - Clinical Laboratory International

Editors and Affiliations

  • CRUK, Paterson Institute for Cancer Research, University of Manchester, Manchester, UK

    Tim Illidge

  • Cancer Sciences Division, Southampton General Hospital, Southampton, UK

    Peter W. M. Johnson

Bibliographic Information

  • Book Title: Lymphoma

  • Editors: Tim Illidge, Peter W. M. Johnson

  • Series Title: Methods in Molecular Medicine

  • DOI: https://doi.org/10.1385/1592599362

  • Publisher: Humana Totowa, NJ

  • eBook Packages: Springer Protocols

  • Copyright Information: Humana Press 2005

  • Hardcover ISBN: 978-1-58829-159-2Published: 17 May 2005

  • Softcover ISBN: 978-1-61737-395-4Published: 10 November 2010

  • eBook ISBN: 978-1-59259-936-3Published: 02 February 2008

  • Series ISSN: 1543-1894

  • Series E-ISSN: 1940-6037

  • Edition Number: 1

  • Number of Pages: XVIII, 342

  • Number of Illustrations: 43 b/w illustrations

  • Topics: Cancer Research

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