Bone Regeneration and Repair

1. Front Matter

   Pages i-xii

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2. Bone Dynamics

   • Jeffrey O. Hollinger

   Pages 1-19

3. Fracture Repair

   • Charles Sfeir, Lawrence Ho, Bruce A. Doll, Kodi Azari, Jeffrey O. Hollinger

   Pages 21-44

4. Common Molecular Mechanisms Regulating Fetal Bone Formation and Adult Fracture Repair

   • Theodore Miclau, Richard A. Schneider, B. Frank Eames, Jill A. Helms

   Pages 45-55

5. Biology of Bone Grafts

   • Victor M. Goldberg, Sam Akhavan

   Pages 57-65

6. Cell-Based Strategies for Bone Regeneration

   • Scott P. Bruder, Tony Scaduto

   Pages 67-92

7. Biology of the Vascularized Fibular Graft

   • Elizabeth Joneschild, James R. Urbaniak

   Pages 93-112

8. Growth Factor Regulation of Osteogenesis

   • Stephen B. Trippel

   Pages 113-132

9. Grafts and Bone Graft Substitutes

   • Doug Sutherland, Mathias Bostrom

   Pages 133-156

10. Gene Transfer Approaches to Enhancing Bone Healing

    • Oliver Betz, Mark Vrahas, Axel Baltzer, Jay R. Lieberman, Paul D. Robbins, Christopher H. Evans

    Pages 157-168

11. Bone Morphogenetic Proteins and Other Growth Factors to Enhance Fracture Healing and Treatment of Nonunions

    • Calin S. Moucha, Thomas A. Einhorn

    Pages 169-194

12. The Ilizarov Technique for Bone Regeneration and Repair

    • James Aronson

    Pages 195-223

13. Biology of Spine Fusion

    • K. Craig Boatright, Scott D. Boden

    Pages 225-239

14. Bone Allograft Transplantation

    • Henry J. Mankin, Francis J. Hornicek, William W. Tomford, Mark C. Gebhardt

    Pages 241-261

15. Bone Grafting for Total Joint Arthroplasty

    • Moussa Hamadouche, Daniel A. Oakes, Daniel J. Berry

    Pages 263-289

16. Biophysical Stimulation Using Electrical, Electromagnetic, and Ultrasonic Fields

    • James T. Ryaby

    Pages 291-309

17. Vascularized Fibula Grafts

    • Richard S. Gilbert, Scott W. Wolfe

    Pages 311-336

18. Craniofacial Repair

    • Bruce A. Doll, Charles Sfeir, Kodi Azari, Sarah Holland, Jeffrey O. Hollinger

    Pages 337-358

19. Bone Regeneration Techniques in the Orofacial Region

    • Samuel E. Lynch

    Pages 359-390

20. Back Matter

    Pages 391-398

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This collection of articles by leading orthopedic and craniofacial surgeons and researchers comprehensively reviews the biology of bone formation and repair, the basic science of autologous bone graft, allograft, bone substitutes, and growth factors, and explore their clinical application in patients with bone repair problems.

• arthroplasty
• bone
• clinical application
• development
• dynamics
• fracture
• growth
• growth factor
• joint
• morphogenesis
• patients
• protein
• proteins
• therapy
• transplantation

From the reviews:

"...Drs. Lieberman and Friedlaender have done an excellent job constructing and organizing the chapters so that all of the key topics such as the biology of bone grafts, bone graft substitutes, gene therapy, and the application of bone grafts in a variety of clinical settings are presented." -Journal of Bone & Joint Surgery

"...anyone who is actively engaged in basic or clinical research on topics related to bone regerenation and repair would be well served to have a copy." -Journal of Bone & Joint Surgery

"This book written by US experts provides current knowledge on the biology of bone formation and repair. … It is of interest to scientists in the field of bone physio-pathology, orthopedic surgeons and those working with musculo-skeletal system such as physiotherapists, sport physicians, as well as pediatricians seeing patients with bone anomalies." (Pediatric Endocrinology Reviews, Vol. 3 (1), 2005)

• Department of Orthopaedic Surgery David Geffen School of Medicine, University of California, Los Angeles

  Jay R. Lieberman

• Department of Orthopaedics and Rehabilitation, Yale University School of Medicine, New Haven

  Gary E. Friedlaender

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