Parkinson's Disease and Nonmotor Dysfunction

1. Front Matter

   Pages i-xii

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2. Behavioral Dysfunction in Parkinson’s Disease

   1. Front Matter

      Pages 1-1

      PDF

   2. Depression

      • William J. Burke, Steven P. Wengel, Daryl Bohac

      Pages 3-12

   3. Anxiety

      • Hubert H. Fernandez, Tanya Simuni

      Pages 13-23

   4. Obsessionality

      • Marie-Andrée Bruneau

      Pages 25-34

   5. Dementia

      • Patricia Kavanagh, Karen Marder

      Pages 35-47

   6. Psychosis

      • Eric S. Molho, Stewart A. Factor

      Pages 49-74

   7. Postsurgical Behavioral Changes

      • Laurie M. Rilling, John A. Lucas, Ryan J. Uitti

      Pages 75-92

3. Autonomic Dysfunction in Parkinson’s Disease

   1. Front Matter

      Pages 93-93

      PDF

   2. Dysphagia

      • Norman A. Leopold

      Pages 95-103

   3. Gastric Dysfunction

      • Tanya Gurevich, Amos D. Korczyn, Nir Giladi

      Pages 105-113

   4. Intestinal Dysfunction

      • Ronald F. Pfeiffer

      Pages 115-125

   5. Impaired Sexual Function

      • Cheryl Waters, Janice Smolowitz

      Pages 127-137

   6. Urological Dysfunction

      • Carlos Singer

      Pages 139-148

   7. Cardiovascular Autonomic Dysfunction

      • David S. Goldstein

      Pages 149-157

   8. Thermoregulatory Dysfunction

      • Mark S. LeDoux

      Pages 159-172

   9. Respiratory Dysfunction

      • Holly A. Shill

      Pages 173-178

4. Sleep-Related Dysfunction in Parkinson’s Disease

   1. Front Matter

      Pages 179-179

      PDF

   2. Insomnia

      • Maria L. Moro-de-Casillas, David E. Riley

      Pages 181-189

   3. Rapid Eye Movement Sleep Behavior Disorder

      • Suzanne Stevens, Cynthia Comella

      Pages 191-198

Parkinson’s Disease and Nonmotor Dysfunction fills a major gap in the current rapidly growing body of knowledge concerning Parkinson’s disease. Drs. Pfeiffer and Bodis-Wollner have correctly perceived that many nonmotor features of Parkinson’s disease are given insufficient attention in the medical literature. Unfortunately, they are often also given insufficient attention by the practicing neurologists who see these patients. As recently pointed out, there is clearly much more to Parkinson’s disease than depletion of the nigrostriatal dopamine system (1). Parkinson’s disease (not just m- tiple system atrophy) is a multisystem disorder, both pathologically and in its clinical manifestations. This is clearly true for the various motor system abnormalities, which are not fully corrected by dopamine replacement therapy strategies, but also for the nonmotor system abnormalities that are the subject of this volume. Although recently there has been increased awareness of the cognitive, psychiatric, and sleep disorders commonly associated with Parkinson’s disease, many of their manifestations remain under-recognized and their importance in managing patients is underestimated. Even less attention is paid to the myriad of other nonmotor disturbances that plague these patients. For example, among the autonomic disorders, although orthostatic hypotension is well recognized, it is usually attributed to dopaminergic medications rather than to effects of the underlying disease. Urologic disorders are also very familiar in these patients, but may not be properly understood or well managed.

• Anxiety
• Apathy
• Autonomic Dysfunction
• Cardiovascular Autonomic Dysfunction
• Dementia
• Dental Dysfunction
• Depression
• Dysfunction
• Dysphagia
• Excessive Daytime Sleepiness
• Fatigue
• Gastric Dysfunction
• Impaired Sexual Function
• Insomnia
• Intestinal Dysf

• Department of Neurology, University of Tennessee Health Science Center, Memphis

  Ronald F. Pfeiffer

• Department of Neurology, State University of New York, Downstate Medical Center, Brooklyn

  Ivan Bodis-Wollner

• Department of Ophthalmology, State University of New York, Downstate Medical Center, Brooklyn

  Ivan Bodis-Wollner

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