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Dopamine and Glutamate in Psychiatric Disorders

  • Book
  • © 2005

Overview

Editors:
  1. Werner J. Schmidt

    1. Department of Neuropharmacology Zoological Institute, University of Tübingen, Tübingen, Germany

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  2. Maarten E. A. Reith

    1. Department of Psychiatry, New York University School of Medicine, New York

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Table of contents (24 chapters)

  1. Front Matter

    Pages i-xiv
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  2. Dopamine

    1. Front Matter

      Pages 1-1
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    2. Dopamine Receptors

      • Kim A. Neve
      Pages 3-43

    3. Dopamine Receptor Alternative Splicing

      • Neil M. Richtand, Laurel M. Pritchard, Lique M. Coolen
      Pages 45-61

  3. Glutamate

    1. Front Matter

      Pages 63-63
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    2. Glutamatergic Pathways

      • Yoland Smith
      Pages 65-77

    3. Glutamate Receptors

      • Daniel T. Monaghan, Julia C. A. More, Bihua Feng, David E. Jane
      Pages 79-116

    4. Metabotropic Glutamate Receptors

      • Krystyna Ossowska
      Pages 117-149

  4. Schizophrenia

    1. Front Matter

      Pages 151-151
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    2. Dopamine and Schizophrenia

      • Bart A. Ellenbroek
      Pages 153-168

    3. Glutamate and Schizophrenia and the N-Methyl-d-Aspartate Receptor Hypofunction Hypothesis

      • Stefan Bleich, Johannes Kornhuber
      Pages 169-179

    4. Role of Glycine in Schizophrenia

      • Beate D. Kretschmer
      Pages 181-195

  5. Depression

    1. Front Matter

      Pages 197-197
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    2. Dopamine and Depression

      • Phil Skolnick
      Pages 199-214

    3. Glutamate and Depression

      • Joaquín Del Río, Diana Frechilla
      Pages 215-234

  6. Stress and Aggression

    1. Front Matter

      Pages 235-235
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    2. Dopamine, Glutamate, and Aggression

      • Klaus A. Miczek, Eric W. Fish
      Pages 237-263

  7. Anxiety

    1. Front Matter

      Pages 265-265
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    2. Glutamatergic Systems and Anxiety

      • David N. Stephens
      Pages 267-289

  8. Attention Deficit Hyperactivity Disorder

    1. Front Matter

      Pages 291-291
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Keywords

About this book

An illuminating summary of our current understanding of the interactive role of dopamine and glutamate in psychiatric diseases and the therapeutic strategies and possibilities for future treatment. Among the new ideas presented are hypotheses on the role of dopamine and glutamate in aggression, the glutamate system in anxiety disorders, glutamate and neurodegeneration, and on the origin and progression of Parkinson's disease. Additional chapters offer novel insights into a variety of psychiatric diseases, including ADHD, stress, aggression, addiction, schizophrenia, depression, social phobias, dementias, bulimia, and neurodegenerative diseases like Parkinson's and Alzheimer's diseases. Each chapter summarizes the prevalence and symptoms of the disease and explains the involvement of dopamine and/or glutamate systems using the newer molecular approaches such as transgenic knockout or knockin mice and recent brain imaging techniques.

Reviews

"...offers an excellent review of our understanding of how dopamine and glutamate influence the pathophysiology of psychiatric disease...an impressive effort, and every psychiatrist (and neurologist) should have this book in their reference library." - 4 Stars, Doody's Health Sciences and Book Review Journal

Editors and Affiliations

  • Department of Neuropharmacology Zoological Institute, University of Tübingen, Tübingen, Germany

    Werner J. Schmidt

  • Department of Psychiatry, New York University School of Medicine, New York

    Maarten E. A. Reith

Bibliographic Information

  • Book Title: Dopamine and Glutamate in Psychiatric Disorders

  • Editors: Werner J. Schmidt, Maarten E. A. Reith

  • DOI: https://doi.org/10.1007/978-1-59259-852-6

  • Publisher: Humana Totowa, NJ

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Humana Press 2005

  • Hardcover ISBN: 978-1-58829-325-1Published: 18 March 2005

  • Softcover ISBN: 978-1-61737-495-1Published: 25 December 2011

  • eBook ISBN: 978-1-59259-852-6Published: 21 April 2010

  • Edition Number: 1

  • Number of Pages: XIV, 600

  • Number of Illustrations: 57 b/w illustrations

  • Topics: Psychiatry

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