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Pancreatic Cancer

Methods and Protocols

  • Book
  • © 2005

Overview

Part of the book series: Methods in Molecular Medicine (MIMM, volume 103)

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Table of contents (20 protocols)

Keywords

About this book

Pancreatic ductal adenocarcinoma is the fourth leading cause of cancer death in the United States. Annually approximately 30,000 Americans are diagnosed with the disease and most will die from it within five years. P- creatic ductal adenocarcinoma is unique because of its late onset in age, high mortality, small tumor samples infiltrated with normal cells, and a lack of both early detection and effective therapies. Some of these characteristics have made studying this disease a challenge. Pancreatic cancer develops as a result of the accumulation of genetic alterations in cancer-causing genes, such as the oncogenes and the tumor-s- pressor genes. In the last decade, major progress has been made in identifying important oncogenes and tumor-suppressor genes for the disease. In Panc- atic Cancer: Methods and Protocols, we review the classical techniques that have contributed to the advances in pancreatic research and introduce new strategies that we hope will add to future breakthroughs in the field of cancer biology. Pancreatic Cancer: Methods and Protocols provides a broad range of protocols for molecular, cellular, pathological, and statistical analyses of s- radic and familial pancreatic cancer. It covers topics from in vitro cell c- tures to in vivo mouse models, DNA to protein manipulation, and mutation analyses to treatment development. We believe that our book will prove an invaluable source of proven protocols for those who are interested in either basic or translational research in pancreatic cancer.

Reviews

"...a worthwhile contribution from a team of experts." Doody's Health Sciences and Book Review Journal

"...a welcome addition to the field...an excellent collection of protocols for a broad range of advanced techniques relevant to many aspects of pancreatic cancer research." -Karger

Editors and Affiliations

  • Departments of Otolaryngology/Head and Neck Surgery and Pathology, Columbia University, New York

    Gloria H. Su

Bibliographic Information

  • Book Title: Pancreatic Cancer

  • Book Subtitle: Methods and Protocols

  • Editors: Gloria H. Su

  • Series Title: Methods in Molecular Medicine

  • DOI: https://doi.org/10.1385/1592597807

  • Publisher: Humana Totowa, NJ

  • eBook Packages: Springer Protocols

  • Copyright Information: Humana Press 2005

  • Hardcover ISBN: 978-1-58829-107-3Published: 12 November 2004

  • Softcover ISBN: 978-1-61737-362-6Published: 09 November 2010

  • eBook ISBN: 978-1-59259-780-2Published: 01 February 2008

  • Series ISSN: 1543-1894

  • Series E-ISSN: 1940-6037

  • Edition Number: 1

  • Number of Pages: XII, 352

  • Topics: Oncology

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