Cellular Drug Delivery

1. Front Matter

   Pages i-x

   PDF

2. Introduction to Cellular Drug elivery

   1. Introduction to Cellular Drug Delivery

      • Kinam Park

      Pages 1-5

3. Fundamentals of Cell Biology and Cellular Drug Delivery

   1. Front Matter

      Pages 7-7

      PDF

   2. Cellular Structure, Function, and Membrane Transport

      • Emily Ware, D. Robert Lu, Svein Øie

      Pages 9-23

   3. Cellular Growth, Development, and Defensive Response

      • Yan Huang, Guangliang Pan, Svein Øie, D. Robert Lu

      Pages 25-41

4. Principles of Cellular Drug Delivery

   1. Front Matter

      Pages 43-43

      PDF

   2. Augmentation of Cell-Mediated Immunity to Virus

      • Erica L. Woodahl, Rodney J. Y. Ho

      Pages 45-65

   3. Development of Nonviral DNA Delivery Systems

      • Hans E. J. Hofland, Frank L. Sorgi, Edward G. Spack

      Pages 67-80

   4. Nucleic Acid Cellular Delivery

      • Wu Xiao, Chun Zhang, Preeti Yadava, Jeffrey Hughes

      Pages 81-94

   5. TAT and TAT-Like Peptides for Protein Transduction and Intracellular Drug Delivery

      • Min Jae Lee, Dexi Liu, Guisheng Zhang, Xiang Gao

      Pages 95-106

   6. Carrier-Mediated Mechanisms for Cellular Drug Transport

      • Antara Banerjee, Jeffrey S. Johnston, Peter W. Swaan

      Pages 107-128

   7. ABC Transporter Proteins and Cellular Drug Resistance

      • William W. Johnson

      Pages 129-162

   8. Human Intestinal Cellular Characteristics and Drug Permeability

      • James E. Polli, Anand Balakrishnan, Paul R. Seo

      Pages 163-180

   9. Targeted Drug Delivery to Tumor Cells Using Colloidal Carriers

      • Sushma Kommareddy, Mansoor Amiji

      Pages 181-215

   10. Biological Protein Nanostructures and Targeted Drug Delivery

       • Guangliang Pan, Svein Øie, D. Robert Lu

       Pages 217-233

5. Practice and Technology of Cellular Drug Delivery

   1. Front Matter

      Pages 235-235

      PDF

   2. Formulation Considerations for DNA-Based Therapeutics

      • Thomas J. Anchordoquy, Taylor K. Armstrong, Marion d. C. Molina, S. Dean Allison, Ye Zhang, Mayank M. Patel et al.

      Pages 237-263

   3. Cationic Microparticles and Emulsions As Effective Delivery Systems for Immune Stimulatory CpG DNA

      • Derek T. O’Hagan, Manmohan Singh, Jeffrey B. Ulmer

      Pages 265-276

   4. Transdermal Delivery of Antisense Oligonucleotides

      • WeiQi Lin, Michel Cormier, Peter E. Daddona

      Pages 277-285

   5. Fc Receptor Targeting With Recombinant Immunoglobulins and Immunoglobulin Formulations

      • Adrian Bot, Dan Smith

      Pages 287-310

An authoritative and up-to-date survey of the fundamental principles, and practice of drug delivery at the cellular level. On the principles side, the authors discuss the broad spectrum of cellular delivery, ranging from coverage of cell-mediated immunity, gene delivery, and protein targeting, to cellular drug transport, cellular drug permeability, and a variety of carrier system related to targeted drug delivery. On the practice side, the authors focus on technological developments in cellular drug delivery, including novel formulations for the delivery of DNA and antisense oligonucleotides ,as well as drug targeting with immunoglobulin formulations and antibody-mediated approaches.

• biology
• cancer
• cancer therapy
• delivery
• development
• drug
• drug delivery
• drug resistance
• future
• research
• resistance

• School of Pharmacy, Temple University, Philadelphia, USA

  D. Robert Lu

• College of Pharmacy, University of Georgia, Athens, USA

  Svein Øie

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