Overview
- Editors:
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Robert J. Soiffer
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Division of Hematologic Malignancies, Dana-Farber Cancer Institute, Harvard Medical School, Boston, USA
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Table of contents (22 chapters)
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Transplant for Malignant Disease
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- Sandra Cohen, Stephen J. Forman
Pages 3-24
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- Humberto Caldera, Sergio Giralt
Pages 25-45
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- Thomas J. Kenney, John W. Sweetenham
Pages 47-84
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- Faith E. Davies, Kenneth C. Anderson
Pages 85-97
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- Yago Nieto, Elizabeth J. Shpall
Pages 99-132
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Complications of Transplantion
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Front Matter
Pages 133-133
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- Takanori Teshima, James L. M. Ferrara
Pages 135-157
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- Uwe Platzbecker, H. Joachim Deeg
Pages 159-184
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- Georgia B. Vogelsang, Colleen H. McDonough
Pages 185-200
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- Lindsey Baden, Robert H. Rubin
Pages 237-258
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- Stephen Gottschalk, Cliona M. Rooney, Helen E. Heslop
Pages 259-270
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Sources of Donor Stem Cells
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Front Matter
Pages 335-335
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- Corey Cutler, Joseph H. Antin
Pages 337-356
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About this book
A comprehensive survey of the current state-of-the-art in hematopoietic stem cell transplantation for malignant disease. The authors focus on the indications and results of transplantation for acute leukemia, chronic myelogenous leukemia, lymphoma, multiple myeloma, and breast cancer. Special attention is given to transplant-related complications, including the pathophysiology and clinical consequences of acute and chronic GVHD, delayed immune reconstitution leading to infectious complications, and organ damage to the lung and liver. Additional chapters address the sources of stem cells and the effects of graft manipulation used to eliminate residual contaminating tumor cells in autologous transplantation, or to reduce the number of T lymphocytes causing GVHD in allogenic transplantation.
Reviews
"Current transplant approaches to the individual hematologic malignancies are discussed and the literature critiqued. The diverse complications of transplantation are discussed in considerable detail; the authors clearly define the underlying pathophysiology as well as state-of-the-art treatment approaches. Chapters on the new field of alternative graft sources is one of the book's best features and include unrelated, haploidentical and umbilical cord transplantation. This is a high-quality publication that is easy to read and not as overwhelming as the larger, more comprehensive transplant books. It is full of helpful information and references. "-Doody's Health Sciences Book Review Journal
"This book provides a timely update and a valuable summary of this rapidly evolving field." -Annals of Internal Medicine
"...a comprehensive review of the current state of the art in hematopoietic setm-cell transplantation for hematologic cancers and breast cancer...belongs in every facility that performs hematopoietic stem-cell transplantation." - New England Journal of Medicine
Editors and Affiliations
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Division of Hematologic Malignancies, Dana-Farber Cancer Institute, Harvard Medical School, Boston, USA
Robert J. Soiffer