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Table of contents (22 chapters)
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Front Matter
About this book
5-fluorouracil, and the new generation of antifolates-the thymidylate synthase and glycinamide ribonucleotide formyltransferase inhibitors. In addition, they review in depth the modulation of antifolate drugs, folate and antifolate transport mechanisms, polyglutamation, resistance, and drug combinations, as well as pharmacogenomics, pharmacodynamics, regulation of gene expression, and mechanisms of cell death.
The wide and progressive scope of Antifolate Drugs in Cancer Therapy provides entré to exciting new avenues for future research, and constitutes a new standard reference for all basic scientists and clinicians engaged in cancer therapeutics.
Editors and Affiliations
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The Cancer Research Campaign Centre for Cancer Therapeutics, The Institute of Cancer Research, Sutton, Surrey, UK
Ann L. Jackman
Bibliographic Information
Book Title: Antifolate Drugs in Cancer Therapy
Editors: Ann L. Jackman
Series Title: Cancer Drug Discovery and Development
DOI: https://doi.org/10.1007/978-1-59259-725-3
Publisher: Humana Totowa, NJ
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eBook Packages: Springer Book Archive
Copyright Information: Springer Science+Business Media New York 1999
Hardcover ISBN: 978-0-89603-596-6Published: 22 January 1999
Softcover ISBN: 978-1-4757-4521-4Published: 24 March 2013
eBook ISBN: 978-1-59259-725-3Published: 22 January 1999
Series ISSN: 2196-9906
Series E-ISSN: 2196-9914
Edition Number: 1
Number of Pages: X, 456
Number of Illustrations: 13 b/w illustrations
Topics: Pharmacy