Overview
- Editors:
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Barrett J. Rollins
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Department of Adult Oncology, Dana-Farber Cancer Institute, Boston, USA
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Table of contents (16 chapters)
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Chemokine Physiology
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- Steven L. Kunkel, Nicholas W. Lukacs, Robert M. Strieter, Theodore Standiford, Stephen W. Chensue
Pages 3-19
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Tumor Infiltration by Leukocytes
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- Alberto Mantovani, Annunciata Vecchi, Silvano Sozzani, Antonio Sica, Paola Allavena
Pages 35-49
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- Ghislain Opdenakker, Jo Van Damme
Pages 51-69
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Modulation of Host Responses to Cancer
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- Barrett J. Rollins, Howard A. Fine, Long Gu, Kenzo Soejima, Susan Tseng
Pages 95-113
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- Thomas A. Hamilton, Charles S. Tannenbaum, James Finke, Ronald Bukowski
Pages 115-126
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Chemokines and Tumor Growth, Metastasis, and Angiogenesis
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Front Matter
Pages 127-127
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- Ji Ming Wang, Weipin Shen, Oleg Chertov, Jo Van Damme, Joost J. Oppenheim
Pages 129-141
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- Robert M. Strieter, Bruno DiGiovine, Peter J. Polverini, Steven L. Kunkel, Armen Shanafelt, Joseph Hesselgesser et al.
Pages 143-167
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- Ann Richmond, Hamid Haghnegahdar, Rebecca Shattuck-Brandt, Lauren D. Wood, Chaitanya S. Nirodi, James D. Owen et al.
Pages 169-189
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Chemokines and Specific Malignancies
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Front Matter
Pages 191-191
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- Rupert P. M. Negus, Frances R. Balkwill
Pages 193-205
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- Frank Rösl, Kerstin Kleine-Lowinski, Harald zur Hausen
Pages 207-225
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- Teizo Yoshimura, Jun-ichi Kuratsu
Pages 227-241
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- Jean E. Crabtree, Ivan J. D. Lindley
Pages 243-259
About this book
Chemokines and Cancer synthesizes a state-of-the-art understanding of the role that chemokines and their receptors play in the pathophysiology of malignancy. It examines the influence of chemokines on a broad array of malignant cells, including their effects on such intrinsic properties as growth and movement, as well as exploring their influence on the host's response to a growing tumor. The authors also demonstrate the physiological consequences of chemokine expression and suggest how chemokines can be used to regulate tumor growth in vivo, including their direct effects on tumor growth, on tumor destruction by host inflammatory cells, and on tumor angiogenesis. The only book available that relates chemokines to cancer, Chemokines and Cancer holds out the promise of novel therapeutic approaches to malignancy through the manipulation of chemokines and/or their receptors.
Reviews
". . .succeeds in bringing to the fore the important notion of whether chemokine action in tumor development should be antagonized or promoted for therapeutic purpose. . .should be well read."-Cell
". . .a detailed account of what is known of the biology of chemokines in cancer and it provides a very useful summary of the topic."-Molecular Pathology
"...this book is a good collection on a complex subject. It should be useful for both beginners and experts." -Cell Biology International
Editors and Affiliations
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Department of Adult Oncology, Dana-Farber Cancer Institute, Boston, USA
Barrett J. Rollins