Gastrointestinal Endocrinology

1. Front Matter

   Pages i-x

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2. Introduction

   1. Introduction

      • Alison M. J. Buchan

      Pages 1-30

3. Biochemistry, Pharmacology, and Receptor Biology

   1. Front Matter

      Pages 31-31

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   2. Biosynthesis and Processing of Gastrointestinal Peptide Hormones

      • Margery C. Beinfeld

      Pages 33-63

   3. Mechanisms That Attenuate Signaling By Regulatory Peptides

      • Stephan Böhm, Eileen F. Grady, Nigel W. Bunnett

      Pages 65-100

   4. Cellular and Molecular Targets of Gastrin

      • Nadya Tarasova

      Pages 101-123

   5. Receptors for Peptides of the VIP/PACAP and PYY/NPY/PP Families

      • Marc Laburthe, Alain Couvineau, Thierry Voisin

      Pages 125-157

4. Regulatory Mechanisms and Systems: Physiology and Pathophysiology

   1. Front Matter

      Pages 159-159

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   2. Cholecystokinin

      • Helen E. Raybould

      Pages 161-168

   3. Effects of Aging on Gut Hormones

      • Tien C. Ko, James C. Thompson

      Pages 169-187

   4. Gastrointestinal Hormones and Gastrointestinal Cancer Growth

      • Yan-Shi Guo, Courtney M . Townsend Jr.

      Pages 189-214

   5. Intraluminal Regulatory Peptides and Intestinal Cholecystokinin Secretion

      • Alan W. Spannagel, Gary M. Green

      Pages 215-241

   6. Neuroendocrine Control of the Exocrine Pancreas

      • David C. Whitcomb

      Pages 243-263

   7. Neuroendocrine Immune Axis in the Intestine

      • Sang K. Park, M. Sue O’Dorisio

      Pages 265-297

   8. Neuroendocrine Regulation of Intestinal Peristalsis

      • J. R. Grider, A. E. Foxx-Orenstein

      Pages 299-319

   9. Pancreatic Polypeptide and Glucose Metabolism

      • Neal E. Seymour, Dana K. Andersen

      Pages 321-334

   10. Peptide Release from the Upper Small Intestine

       • Jean-Claude Cuber

       Pages 335-351

   11. Regulation of Gastric Acid Secretion

       • Wolfgang E. Schmidt, Jerzy B. Bójko

       Pages 353-391

   12. Role of Cholecystokinin in Physiologic and Pathophysiologic Growth of the Pancreas

       • Craig D. Logsdon

       Pages 393-422

5. Gut Peptides

   1. Front Matter

      Pages 423-423

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Leading clinical and basic science researchers present the latest molecular and cellular findings on key gut peptides, illuminating their physiology and pathophysiology, as well as highlighting the regulatory mechanisms underlying their action in the intestinal tract. The book focuses on gut peptide physiology and receptor pharmacology, gut processing and receptor biology, and on regulatory mechanisms in the gut, including pancreatic feedback mechanisms. Also included are chapters on the trophic effects of gut peptides on GI and pancreatic cancer; the regulation of gut peptide gene expression; and gastric secretion, especially in diseased states.

• G proteins
• Pancreas
• biosynthesis
• cancer
• growth
• growth factor
• hormone
• insulin-like
• metabolism
• pancreatic cancer
• pathophysiology
• pharmacology
• physiology
• protein
• small intestine

"... the book contains a wealth of material...The authors are experts in the field, and they have done a thorough job in covering their topics...This book is an excellent reference on gut hormones..."-The Quarterly Review of Biology

• Department of Surgery, The University of Texas Medical Branch, Galveston, USA

  George H. Greeley

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