Overview
- Editors:
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Stephen B. Dunnett
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University of Cambridge, Cambridge, UK
Cardiff University, Cardiff, UK
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Alan A. Boulton
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University of Saskatchewan, Saskatoon, Canada
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Glen B. Baker
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University of Alberta, Edmonton, Canada
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Table of contents (23 protocols)
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Sources of Cells for Transplantation
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- Stephen B. Dunnett, Anders Björklund
Pages 3-25
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- Siddharthan Chandran, Clive N. Svendsen
Pages 41-54
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- Vincent M. Mann, John D. Sinden
Pages 55-72
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- Alison E. Willing, Paul R. Sanberg
Pages 73-88
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- Ronald J. Mandel, Steve Hardy, Richard O. Snyder, Luigi Naldini, Stuart E. Leff
Pages 103-130
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Methods of Implantation
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Front Matter
Pages 131-131
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- Stephen B. Dunnett, Anders Björklund
Pages 133-148
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- Anthony J. Castro, Jens Zimmer
Pages 169-194
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- Roger A. Barker, Anne E. Rosser, Stephen B. Dunnett
Pages 195-205
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- Guido Nikkhah, Christian Winkler, Alexandra Rödter, Madjid Samii
Pages 207-231
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- Dwaine F. Emerich, Shelley R. Winn
Pages 233-277
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- Robin J. M. Franklin, William F. Blakemore
Pages 305-317
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Factors in Graft Survival and Function
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Front Matter
Pages 363-363
About this book
we might seek alternative sources of donor tissues. Genetic en- neering, expansion of precursor cells, generation of immortalized cell lines, and transplantation between species are all under active investigation. Although significant difficulties remain for each of these alternatives, the problems appear soluble and relevant knowledge is expanding rapidly. As we enter the twenty-first century, the place of neural tra- plantation in experimental neuroscience is continuing to evolve. Rather than being a topic in its own right, neural transplantation increasingly serves as just another technique in the researcher's armory--alongside lesions, pharmaceuticals, gene transfer, and a variety of other techniques--for the experimental manipulation of brain structure and function. This is particularly true for studies of degeneration, plasticity, regeneration, and recovery of function in the nervous system, topics of increasing importance as experimental neurobiology is required to serve the higher needs of neurological and mental health in aging societies. Within this evolving context, Neural Transplantation Methods seeks to serve a particular need: to provide experimental neu- scientists with a source book of information to enable them to select and adapt transplantation techniques to their own expe- mental programs. All authors have been asked to address prac- cal issues, to enable the reader to assess what is available, what are the alternatives, what are the practical issues to be resolved in applying a particular protocol and getting it to work reliably in their unique experimental context.
Reviews
"...a book with so much information is very valuable for neuroscientists."- Clinical Neurology and Neurosurgery
"Neural Transplantation Methods seeks to serve a particular need: to provide experimental neuroscientists with a source book of information to enable them to select and adapt transplantation techniques to their own experimental programs....Neural Transplantation Methods is a very interesting, up-to-date, and complete book on the technical and methodological issues in relation with experimental neural transplantation. It is a perfect source book of information for those who want to include the transplantation strategy in their experimental program." - Acta Neurologica Belgica
Editors and Affiliations
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University of Cambridge, Cambridge, UK
Stephen B. Dunnett
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Cardiff University, Cardiff, UK
Stephen B. Dunnett
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University of Saskatchewan, Saskatoon, Canada
Alan A. Boulton
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University of Alberta, Edmonton, Canada
Glen B. Baker
