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Neurotransmitter Transporters

Structure, Function, and Regulation

  • Book
  • © 1997

Overview

Editors:
  1. Maarten E. A. Reith

    1. College of Medicine, University of Illinois, Peoria, USA

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Part of the book series: Contemporary Neuroscience (CNEURO)

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Table of contents (12 chapters)

  1. Front Matter

    Pages i-x
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  2. The Structure and Function of Norepinephrine, Dopamine, and Serotonin Transporters

    • Sue L. Povlock, Susan G. Amara
    Pages 1-28

  3. Regulation of Antidepressant-Sensitive Serotonin Transporters

    • Randy D. Blakely, Sammanda Ramamoorthy, Yan Qian, Sally Schroeter, Christopher C. Bradley
    Pages 29-72

  4. Mechanisms of Biogenic Amine Neurotransmitter Transporters

    • Gary Rudnick
    Pages 73-100

  5. Cloned Sodium- (and Chloride-) Dependent High-Affinity Transporters for GABA, Glycine, Proline, Betaine, Taurine, and Creatine

    • Joshua W. Miller, Daniel T. Kleven, Barbara A. Domin, Robert T. Fremeau Jr.
    Pages 101-150

  6. Sodium-Coupled GABA and Glutamate Transporters

    • Baruch I. Kanner
    Pages 151-169

  7. The High-Affinity Glutamate Transporter Family

    • Yoshikatsu Kanai, Davide Trotti, Stephan Nussberger, Matthias A. Hediger
    Pages 171-213

  8. Vesicular Neurotransmitter Transporters

    • Shimon Schuldiner
    Pages 215-240

  9. Neurotransmitter Transporter Proteins

    • Amrat P. Patel
    Pages 241-262

  10. Dopamine Transporter Uptake Blockers

    • F. Ivy Carroll, Anita H. Lewin, Michael J. Kuhar
    Pages 263-295

  11. Imaging Transporters for Dopamine and Other Neurotransmitters in Brain

    • Michael J. Kuhar, F. Ivy Carroll, Anita H. Lewin, John W. Boja, Ursula Scheffel, Dean F. Wong
    Pages 297-313

  12. The Dopamine Transporter in Human Brain

    • Deborah C. Mash, Julie K. Staley
    Pages 315-343

  13. Role of Axonal and Somatodendritic Monoamine Transporters in Action of Uptake Blockers

    • Nian-Hang Chen, Maarten E. A. Reith
    Pages 345-391

  14. Back Matter

    Pages 393-405
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Keywords

About this book

A comprehensive survey of recent advances made in characterizing neurotransmitter transporters-including their imaging in the living brain-and in elucidating the processes underlying biological transport. The expert contributors present up-to-date findings on the molecular cloning of transporters and on neurotransmitter families both in plasma membranes and in storage vesicles. They also provide essential information on the structure-activity relationships for a multitude of recently synthesized dopamine uptake blockers, on transporter changes in the context of human drug abuse, and on the role of transporters in the action of uptake blockers in vivo. The book opens the new frontier of transporters research, authoritatively presenting new insights into their roles in such diseases as brain ischemia and ALS, and into their involvement as targets for antidepressants, antiepileptics, drugs of abuse, and neurotoxins.

Editors and Affiliations

  • College of Medicine, University of Illinois, Peoria, USA

    Maarten E. A. Reith

Bibliographic Information

  • Book Title: Neurotransmitter Transporters

  • Book Subtitle: Structure, Function, and Regulation

  • Editors: Maarten E. A. Reith

  • Series Title: Contemporary Neuroscience

  • DOI: https://doi.org/10.1007/978-1-59259-470-2

  • Publisher: Humana Totowa, NJ

  • eBook Packages: Springer Book Archive

  • Copyright Information: Humana Press 1997

  • eBook ISBN: 978-1-59259-470-2Published: 01 October 1996

  • Edition Number: 1

  • Number of Pages: X, 405

  • Topics: Neurosciences

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