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Myasthenia Gravis and Related Disorders

  • Book
  • © 2003

Overview

Editors:
  1. Henry J. Kaminski

    1. Departments of Neurology and Neurosciences, University Hospitals of Cleveland, Louis Stokes Cleveland Veterans Affairs Medical Center, Case Western Reserve University, Cleveland, USA

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Part of the book series: Current Clinical Neurology (CCNEU)

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Table of contents (16 chapters)

  1. Front Matter

    Pages i-x
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  2. Neuromuscular Junction Physiology and Pathophysiology

    • Robert L. Ruff
    Pages 1-13

  3. Acetylcholine Receptor Structure

    • Jon M. Lindstrom
    Pages 15-52

  4. Immunopathogenesis of Myasthenia Gravis

    • Bianca M. Conti-Fine, Brenda Diethelm-Okita, Norma Ostlie, Wei Wang, Monica Milani
    Pages 53-91

  5. Clinical Presentation and Epidemiology of Myasthenia Gravis

    • Jan B. M. Kuks, Hans J. G. H. Oosterhuis
    Pages 93-113

  6. Ocular Myasthenia

    • Robert B. Daroff
    Pages 115-128

  7. Thymoma-Associated Myasthenia Gravis

    • Alexander Marx, Philipp Stroebel
    Pages 129-148

  8. Electrodiagnosis of Neuromuscular Junction Disorders

    • Bashar Katirji
    Pages 149-175

  9. Specific Antibodies in the Diagnosis and Management of Autoimmune Disorders of Neuromuscular Transmission and Related Diseases

    • Mark A. Agius, David P. Richman, Angela Vincent
    Pages 177-196

  10. Treatment of Myasthenia Gravis

    • Henry J. Kaminski
    Pages 197-221

  11. Neurocritical Care of Myasthenia Gravis Crisis

    • Jose Americo M. Fernandes Filho, Jose I. Suarez
    Pages 223-234

  12. Thymectomy

    • Alfred Jaretzki III
    Pages 235-267

  13. Lambert-Eaton Syndrome

    • C. Michel Harper, Vanda A. Lennon
    Pages 269-291

  14. Acquired Neuromyotonia

    • Ian Hart, Angela Vincent
    Pages 293-307

  15. Congenital Myasthenic Syndromes

    • Suraj A. Muley, Christopher M. Gomez
    Pages 309-326

  16. Toxic Neuromuscular Transmission Disorders

    • James F. Howard Jr.
    Pages 327-354

  17. Psychological and Social Consequences of Myasthenia Gravis

    • Robert H. Paul, James M. Gilchrist
    Pages 355-371

  18. Back Matter

    Pages 373-396
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Keywords

About this book

An international panel of expert clinicians and leading scientists comprehensively review the clinical and basic science of this disease and its relatives, including acquired neuromytonia and Lambert-Eaton syndrome. For the clinician, the book describes the wide range of signs and symptoms that make these diseases difficult to diagnose, review in depth the available diagnostic methods and their limitations, offer practical treatment recommendations based on years of experience, and discuss several promising treatments now emerging. For the basic scientist, the text illuminates neuromuscular structure and function, describes in detail the acetylcholine receptor (the central target of pathology in myasthenia gravis), and illuminates the autoimmune pathogenesis.

Reviews

"The book covers the physiology of the neuromuscular junction and of the ACR structure with detailed illustrations. There are extensive dissertations on the immunopathogenesis of myasthenia gravis, on the different immunogenetic properties of different thymona types, and finally on the different clinical presentations and therapeutic options. An entire chapter is devoted to when thymectomy is necessary and how it is performed. The chapter on myasthenia gravis crisis is concise and informative. This is a well organized, comprehensive book with abundant up-to-date references. It belongs in the library of any neurologist involved in the care of neuromuscular junction disorders." -Doody's Health Sciences Book Review Journal

"...a well rounded book. I think that neurologists in training and general neurologists wanting a refresher course could do a lot worse then read this text. I would certainly recommend it." - Brain: A Journal of Neurology

"Primarily this book will appeal to neurologists, clinical neurophysiologists, and neuroanaesthetists who will find it useful for their everyday clinical practice; researchers of neuromuscular junction disorders will also find the book interesting. This book is an up-to-date and valuable source of information on myasthenia and related disorders." -The Lancet

"Generally, the chapters are well-written, illustrations are appropriate, and the twenty-first century well represented in the references. The book is useful and up-to-date summary of all aspects of MG and its related disorders." -Muscle & Nerve

"This book is strongly recommended to clinicians and researchers dealing with neuromuscular disorders (and to thoracic surgeons performing thymectomy)." -Journal of Neurology, Neurosurgery, and Psychiatry

Editors and Affiliations

  • Departments of Neurology and Neurosciences, University Hospitals of Cleveland, Louis Stokes Cleveland Veterans Affairs Medical Center, Case Western Reserve University, Cleveland, USA

    Henry J. Kaminski

Bibliographic Information

  • Book Title: Myasthenia Gravis and Related Disorders

  • Editors: Henry J. Kaminski

  • Series Title: Current Clinical Neurology

  • DOI: https://doi.org/10.1007/978-1-59259-341-5

  • Publisher: Humana Totowa, NJ

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer Science+Business Media New York 2003

  • eBook ISBN: 978-1-59259-341-5Published: 03 October 2002

  • Series ISSN: 1559-0585

  • Series E-ISSN: 2524-4043

  • Edition Number: 1

  • Number of Pages: X, 396

  • Number of Illustrations: 34 b/w illustrations, 3 illustrations in colour

  • Topics: Neurology

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