Overview
- Editors:
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Tanja Zigova
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Center for Aging and Brain Repair, Departments of Neurosurgery, Anatomy and Pharmacology, University of South Florida College of Medicine, Tampa, USA
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Evan Y. Snyder
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Department of Neurology, Harvard Medical School, Harvard Institutes of Medicine & Beth Israel-Deaconess Medical Center, Division of Newborn Medicine, Children’s Hospital-Boston, Boston, USA
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Paul R. Sanberg
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Center for Aging and Brain Repair, Departments of Neurosurgery, Neurology, Psychiatry and Pharmacology, University of South Florida College of Medicine, Tampa, USA
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Table of contents (16 chapters)
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Stem Cells for and from the CNS
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- Melissa K. Carpenter, Mark Mattson, Mahendra S. Rao
Pages 3-44
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- Angela Gritti, Angelo Vescovi, Rossella Galli
Pages 45-68
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- Martha Windrem, Neeta Roy, Marta Nunes, Steven A. Goldman
Pages 69-88
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- Eiji Nakagawa, Kozo Hatori, Atsushi Nagai, Hyun B. Choi, Myung A. Lee, Jung H. Bang et al.
Pages 89-106
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- Shijie Song, Paul Sanberg, Juan Sanchez-Ramos
Pages 107-131
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In Vitro and/or In Vivo Manipulations of Stem/Progenitor Cells for the CNS
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Front Matter
Pages 133-133
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- Luciano Conti, Elena Cattaneo
Pages 135-181
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- Dennis A. Steindler, Bjorn Scheffler, Eric D. Laywell, Oleg N. Suslov, Tong Zheng, Thomas Reiniger et al.
Pages 183-201
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- Sanjay S. Magavi, Jeffrey D. Macklis
Pages 229-267
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- Jasodhara Ray, Daniel A. Peterson
Pages 269-286
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Stem/Progenitor Cells in Representative Therapeutic Paradigms for the CNS
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Front Matter
Pages 287-287
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- Kook In Park, James J. Palacino, Roseanne Taylor, Karen S. Aboody, Barbara A. Tate, Vaclav Ourednik et al.
Pages 289-332
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- Yang D. Teng, Mary Katherine White, Erin Lavik, Shaoxiang Liu, Mahesh Lachyankar, Kook In Park et al.
Pages 333-345
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- Paul Lu, Evan Y. Snyder, Mark H. Tuszynski
Pages 347-365
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- Martin Marsala, Osamu Kakinohana, Tony L. Yaksh, Joho Tokumine
Pages 367-393
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- S. Ausim Azizi, Emily J. Schwarz, Darwin Prockop, Guillermo Alexander, Katherine A. Mortati, Barbara Krynska
Pages 395-409
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- Cesario V. Borlongan, Paul R. Sanberg
Pages 411-429
About this book
Active neuroscientists survey NSCs as potential tools for central nervous system and spinal cord repair by explaining their clinically significant fundamental properties, manipulations, and potential therapeutic paradigms. Their discussion of the fundamental biology of NSCs illustrates the signaling pathways that regulate stem cell division and differentiation, and defines the methods of NSC expansion and propagation, neuromorphogenesis, the factors determining cell fate both in vitro and in situ, and the induction of self-reparative processes within the brain. They also present strategies that may lead to fruitful clinical applications in the near future. These range from the replacement of degenerated, dysfunctional, or maldeveloped cells to the provision of factors that may protect, correct, recruit, promote self-repair, or mediate the connectivity of host cells.
Reviews
"The purpose is to address research protocols and possible future applications of neural stem cells in clinical practice. The author has met the objectives. . .Starting from the basic aspects of cell culturing, this book emphasizes the different available research protocols that are currently being used for possible management of neurological degenerative diseases. In addition, molecular mechanisms of interaction are always explained whenever necessary. This book is a perfect purchase for neurologists and neuroscientists. Neurosurgeons with a basic science interest would also find this a useful acquisition."-Doody's Health Sciences Book Review Journal
Editors and Affiliations
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Center for Aging and Brain Repair, Departments of Neurosurgery, Anatomy and Pharmacology, University of South Florida College of Medicine, Tampa, USA
Tanja Zigova
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Department of Neurology, Harvard Medical School, Harvard Institutes of Medicine & Beth Israel-Deaconess Medical Center, Division of Newborn Medicine, Children’s Hospital-Boston, Boston, USA
Evan Y. Snyder
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Center for Aging and Brain Repair, Departments of Neurosurgery, Neurology, Psychiatry and Pharmacology, University of South Florida College of Medicine, Tampa, USA
Paul R. Sanberg