Leading researchers synthesize scattered experimental data to help develop an intimate understanding of how cytokines and chemokines are involved in the pathogenesis of autoimmune diseases. The many chapters offer critical reviews the basic mechanisms controlling cytokine induction and regulation, as well as the resulting production of proinflammatory and anti-inflammatory cytokines, the former of which induces organ-specific autoimmune diseases. From the vantage of these insights, they address the role of cytokines in a wide variety of autoimmune diseases, uvetis, encephalomyelitis, multiple sclerosis, human type 1 diabetes, rheumatoid arthritis, SLE, and myasthenia gravis. Authoritative and state-of-the-art, Cytokines and Autoimmune Disease highlights the enormous therapeutic potential of cytokine modulation in the treatment of autoimmune disease.
Reviews
"Authoritative and state-of-the-art, Cytokines and Autoimmune Disease highlights the enormous therapeutic potential of cytokine modulation in the treatment of autoimmune disease." -Immunology News
Editors and Affiliations
Center for Neurologic Diseases, Brigham and Women’s Hospital, Harvard Medical School, Boston, USA
Vijay K. Kuchroo,
David A. Hafler,
Lindsay B. Nicholson
Department of Immunology, Scripps Research Institute, La Jolla, USA
Nora Sarvetnick
Bibliographic Information
Book Title: Cytokines and Autoimmune Diseases
Editors: Vijay K. Kuchroo, Nora Sarvetnick, David A. Hafler, Lindsay B. Nicholson
