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Table of contents (24 chapters)
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Introduction
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Essential Concepts in Molecular Biology
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Molecular Themes in Oncogenesis
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Mechanisms of Mutation
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Etiology of Human Cancers
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Human Tumor Systems
Keywords
About this book
Internationally renowned basic and clinical scientists provide an account of our best current understanding of the genetics of cancer. These authoritative contributors describe in detail each of the known molecular mechanisms governing neoplastic transformation in the breast, prostate, lung, liver, colon, and skin, and in the leukemias and lymphomas. Their discussion illuminates both recent developments and established concepts in epidemiology, molecular techniques, oncogenesis, and mutation mechanisms, as well as the chemical, viral, and physical mechanisms in cancer induction.
Reviews
"The structure of the book is fairly conventional, with an excellent scene-setting chapter that provides a clear description of widely applied methodologies....The tumor-specific chapters are well written and will attract those with interests in particular tumor-types. The colorectal chapters is especially well written, focussing on how the genetic alterations lead to changes in signal transduction pathways, which underpin disordered growth regulation. All chapters are extensively referenced....the book is well written and should be useful to fellows just about to enter the laboratory to undertake a period of molecular research, and for those established clinicians who require a detailed update on the contribution that molecular biology has made to cancer research." - Annals of Oncology
"This is an excellent volume for both investigators in the field of oncology as well as practicing oncologists." -Quarterly Review of Biology
"This is an excellent volume for both investigators in the field of oncology as well as practicing oncologists." -Quarterly Review of Biology
Editors and Affiliations
Bibliographic Information
Book Title: The Molecular Basis of Human Cancer
Editors: William B. Coleman, Gregory J. Tsongalis
DOI: https://doi.org/10.1007/978-1-59259-125-1
Publisher: Humana Totowa, NJ
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eBook Packages: Springer Book Archive
Copyright Information: Springer Science+Business Media New York 2002
Softcover ISBN: 978-1-61737-107-3Published: 05 November 2010
eBook ISBN: 978-1-59259-125-1Published: 10 August 2001
Edition Number: 1
Number of Pages: XII, 588
Topics: Oncology