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The Melanocortin Receptors

  • Book
  • © 2000

Overview

Editors:
  1. Roger D. Cone

    1. Vollum Institute, Oregon Health Sciences University, Portland, USA

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Part of the book series: The Receptors (REC)

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Table of contents (19 chapters)

  1. Front Matter

    Pages i-x
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  2. Historical Perspectives

    1. Front Matter

      Pages 1-1
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    2. Proopiomelanocortin and the Melanocortin Peptides

      • Alex N. Eberle
      Pages 3-67

    3. Melanocortins and Pigmentation

      • Aaron B. Lerner
      Pages 69-73

    4. Melanocortins and Adrenocortical Function

      • Martine Bégeot, José M. Saez
      Pages 75-107

    5. Effects of Melanocortins in the Nervous System

      • Roger A. H. Adan
      Pages 109-141

    6. Peripheral Effects of Melanocortins

      • Bruce A. Boston
      Pages 143-169

  3. Characterization of the Melanocortin Receptors

    1. Front Matter

      Pages 171-171
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    2. Melanocortin Receptor Expression and Function in the Nervous System

      • Jeffrey B. Tatro
      Pages 173-207

    3. Cloning of the Melanocortin Receptors

      • Kathleen G. Mountjoy
      Pages 209-235

  4. Biochemical Mechanism of Receptor Action

    1. Front Matter

      Pages 237-237
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    2. The Molecular Pharmacology of Alpha-Melanocyte Stimulating Hormone

      • Victor J. Hruby, Guoxia Han
      Pages 239-261

    3. In Vitro Mutagenesis Studies of Melanocortin Receptor Coupling and Ligand Binding

      • Carrie Haskell-Luevano
      Pages 263-306

  5. Receptor Function

    1. Front Matter

      Pages 307-307
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    2. The Melanocortin-1 Receptor

      • Dongsi Lu, Carrie Haskell-Luevano, Dag Inge Vage, Roger D. Cone
      Pages 309-339

    3. The Human Melanocortin-1 Receptor

      • Eugene Healy, Mark Birch-Machin, Jonathan L. Rees
      Pages 341-359

    4. The Melanocortin-2 Receptor in Normal Adrenocortical Function and Familial Adrenocorticotropic Hormone Resistance

      • Adrian J. L. Clark
      Pages 361-383

    5. The Melanocortin-3 Receptor

      • Robert A. Kesterson
      Pages 385-403

    6. The Melanocortin-4 Receptor

      • Roger D. Cone
      Pages 405-447

    7. The Melanocortin-5 Receptor

      • Wenbiao Chen
      Pages 449-472
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Keywords

About this book

Roger Cone and a distinguished team of expert investigators provide the first major treatment of this critically important receptor family. The book illuminates the structure and function of these receptors through a wide-ranging review of the latest findings concerning the biology, physiology, and pharmacology of their peptide ligands and covers the major melanocortin peptides, Melanocortin-1-Receptors through Melanocortin-5-Receptors. Topics include the characterization of the melanocortin receptors, the biochemical mechanism of receptor action, and receptor function and regulation. Timely and authoritative, The Melanocortin Receptors offers an up-to-date knowledge base on the remarkably complex structure and functions of the melanocortins, a guide that will prove invaluable for today's neuroscientists, endocrinologists, pharmacologists, and other clinical and experimental investigators working in this fast moving field.

Reviews

"New data on melanocortin receptors 1-5 and their regulation are the topic of several chapters. A complete, well referenced text of interest to all endocrinologists, neuroscientists, geneticists, physiologists and pharmacologists." - Journal of Pediatric Endocrinology & Metabolism

Editors and Affiliations

  • Vollum Institute, Oregon Health Sciences University, Portland, USA

    Roger D. Cone

Bibliographic Information

  • Book Title: The Melanocortin Receptors

  • Editors: Roger D. Cone

  • Series Title: The Receptors

  • DOI: https://doi.org/10.1007/978-1-59259-031-5

  • Publisher: Humana Totowa, NJ

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer Science+Business Media New York 2000

  • Hardcover ISBN: 978-0-89603-579-9Published: 14 March 2000

  • Softcover ISBN: 978-1-61737-082-3Published: 08 December 2010

  • eBook ISBN: 978-1-59259-031-5Published: 14 March 2000

  • Series ISSN: 1048-6909

  • Series E-ISSN: 2524-6488

  • Edition Number: 1

  • Number of Pages: X, 542

  • Topics: Endocrinology, Medicine/Public Health, general

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