Overview
- Details how electrophysiology can be best utilized in drug discovery and development
- Introduces applications of the dynamic clamp method
- Includes an extensive theoretical treatise concerning single channel kinetic analysis
Part of the book series: Methods in Molecular Biology (MIMB, volume 403)
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Table of contents (19 protocols)
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Pharmacology
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Physiology
Keywords
About this book
Patch Clamp Methods and Protocols surveys the typical patch clamp applications and advises scientists on identifying problems and selecting the best technique in each instance. The experiments described require a basic level of electrophysiological training, and aid the researcher in pursuing new areas of electrophysiology and using the patch clamp technique effectively. Patch Clamp Methods and Protocols is organized by the major areas of patch clamp application: Pharmacology, Physiology, and Biophysics. Individual techniques are explored within the area that they are applied most often. Researchers will find this text to be an invaluable aid in the design and execution of a wide variety of patch clamp experiments, both on their own and in conjunction with other state-of-the-art methodologies.
Reviews
From the reviews:
"This book will be helpful to researchers already working in the field of electrophysiology, but also those coming to this field from pharmacological, physiological, and biophysical areas." - Doody's Book Review Service
"'Patch-clamp: Methods and Protocols’ introduces some common patch-clamp applications. It is intended to assist scientists in identifying problems, which could be best addressed by this technique. The book provides the step-by-step procedures to perform the experiments that answer those questions. … It will be a useful companion for moderately advanced users wishing to extend their skills." (Maria Drigelova, General Physiology and Biophysics, Vol. 27, April, 2008)
Bibliographic Information
Book Title: Patch-Clamp Methods and Protocols
Editors: Peter Molnar, James J. Hickman
Series Title: Methods in Molecular Biology
DOI: https://doi.org/10.1007/978-1-59745-529-9
Publisher: Humana Totowa, NJ
eBook Packages: Springer Protocols
Copyright Information: Humana Press 2007
Hardcover ISBN: 978-1-58829-698-6Published: 19 September 2007
Softcover ISBN: 978-1-61737-724-2Published: 19 November 2010
eBook ISBN: 978-1-59745-529-9Published: 01 October 2008
Series ISSN: 1064-3745
Series E-ISSN: 1940-6029
Edition Number: 1
Number of Pages: XI, 321
Number of Illustrations: 71 b/w illustrations
Topics: Biochemistry, general, Human Physiology, Pharmacology/Toxicology, Biological and Medical Physics, Biophysics, Neurosciences