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Immunotherapy of Cancer

  • Book
  • © 2006

Overview

Editors:
  1. Mary L. Disis

    1. University of Washington School of Medicine, Seattle

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Part of the book series: Cancer Drug Discovery and Development (CDD&D)

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Table of contents (28 chapters)

  1. Front Matter

    Pages i-xii
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  2. Discovery of Target Molecules for Cancer Immunotherapy by Genetic and Bioinformatic Approaches

    • Özlem Türeci, Thorsten Klamp, Michael Koslowski, Sebastian Kreiter, Ugur Sahin
    Pages 1-19

  3. Current Strategies for the Identification of Immunogenic Epitopes of Tumor Antigens

    • Ludmila Müller, Stephanie McArdle, Evelyna Derhovanessian, Thomas Flad, Ashley Knights, Robert Rees et al.
    Pages 21-44

  4. Current and Future Role of Natural-Killer Cells in Cancer Immunotherapy

    • Lisa M. Harlan, Julie Y. Djeu
    Pages 45-58

  5. The Role of Immune Monitoring in Evaluating Cancer Immunotherapy

    • Holden T. Maecker
    Pages 59-72

  6. Statistical Analysis of Immune Response Assays in Cancer Immunotherapy Trials

    • Susan Groshen
    Pages 73-85

  7. DNA Vaccines for Cancer Immunotherapy

    • Heesun Kwak, Howard L. Kaufman
    Pages 87-114

  8. Dendritic Cells

    • Weiping Zou, Tyler J. Curiel
    Pages 115-126

  9. Different Approaches to Dendritic Cell-Based Cancer Immunotherapy

    • Noweeda Mirza, Dmitry Gabrilovich
    Pages 127-138

  10. Anti-Idiotype Antibody Vaccines for the Immunotherapy of Cancer

    • Malaya Bhattacharya-Chatterjee, Nitin Rohatgi, Sunil K. Chatterjee, Asim Saha, Rakesh Shukla, Kenneth A. Foon
    Pages 139-149

  11. Autologous Tumor-Derived Heat Shock Protein Vaccine as a New Paradigm for Individualized Cancer Therapeutics

    • Jie Dai, Zihai Li
    Pages 151-166

  12. Tumor-Reactive T-Cells for Adoptive Immunotherapy

    • Helga Bernhard, Julia Neudorfer, Kerstin Gebhard, Heinke Conrad, Dirk H. Busch, Christian Peschel
    Pages 167-179

  13. T-Cell Adoptive Immunotherapy of Cancer

    • Peter A. Cohen, Mohamed Awad, Suyu Shu
    Pages 181-212

  14. Retroviral-Mediated Gene Transfer for Engineering Tumor-Reactive T-Cells

    • Jeffrey J. Roszkowski, Michael I. Nishimura
    Pages 213-233

  15. Harnessing the Potential of Graft-vs-Tumor

    • Nancy M. Hardy, Michael R. Bishop
    Pages 235-261

  16. Tumor-Induced Immune Suppression and Immune Escape

    • Michael Campoli, Soldano Ferrone
    Pages 263-284

  17. The Tumor Microenvironment

    • George Coukos, Jose-Ramon Conejo-Garcia
    Pages 285-301

  18. Manipulation of Lymphocyte Homeostasis for Enhancing Antitumor Immunity

    • Eduardo Davila, Esteban Celis
    Pages 303-316

  19. Fast-Lane Evolution in the Tumor Microenvironment

    • Gabriella Marincola, Francesco M. Marincola
    Pages 317-329

  20. Manipulating Immunological Checkpoints to Maximize Antitumor Immunity

    • Leisha A. Emens, R. Todd Reilly, Elizabeth M. Jaffee
    Pages 331-353
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Keywords

About this book

Expert bench and clinical scientists join forces to concurrently review both the state-of-the-art in tumor immunology and its clinical translation into promising practical treatments. The authors explain in each chapter the scientific basis behind such therapeutic agents as monoclonal antibodies, cytokines, vaccines, and T-cells, and illustrate their clinical manipulation to combat cancer. Additional chapters address statistical analysis-both of clinical trials and assay evaluations-methods for the discovery of antigens, adoptive T cell therapy, and adaptive and innate immunity. The challenges in clinical trial design, the need for biomarkers of response-such as novel imaging techniques and immunologic monitoring-and the new advances and directions in cancer immunotherapy are also fully examined.

Reviews

From the reviews:

"Immunotherapy of Cancer provides in 28 chapters a comprehensive overview of experimental and clinical achievements in tumor immunology. Each chapter is designed to give the reader the scientific basis behind the discussed therapy and outline basic theory, as well as practical treatment applications. … The book belongs to the successful series of publications Cancer Drug Discovery and Development from Humana Press. It will be of interest to clinicians and to laboratory cancer researchers … ." (Cestmir Altaner, Neoplasma, Vol. 54 (2), March, 2007)

Editors and Affiliations

  • University of Washington School of Medicine, Seattle

    Mary L. Disis

Bibliographic Information

  • Book Title: Immunotherapy of Cancer

  • Editors: Mary L. Disis

  • Series Title: Cancer Drug Discovery and Development

  • DOI: https://doi.org/10.1385/1597450111

  • Publisher: Humana Totowa, NJ

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Humana Press 2006

  • Hardcover ISBN: 978-1-58829-564-4Published: 15 December 2005

  • Softcover ISBN: 978-1-61737-645-0Published: 09 December 2010

  • eBook ISBN: 978-1-59745-011-9Published: 28 October 2007

  • Series ISSN: 2196-9906

  • Series E-ISSN: 2196-9914

  • Edition Number: 1

  • Number of Pages: XII, 516

  • Number of Illustrations: 52 b/w illustrations

  • Topics: Cancer Research

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