Lower Extremity Arterial Disease

1. Front Matter

   Pages i-xiii

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2. Claudication

   • Dennis G. Caralis

   Pages 1-21

3. Noninvasive Diagnostic Evaluation of Peripheral Arterial Disease

   • Nicos Labropoulos, Apostolos K. Tassiopoulos

   Pages 23-38

4. Smoking and Smoking Cessation

   • Albert J. Bellg, Aristdis N. Mavridis

   Pages 39-52

5. Peripheral Arterial Disease and Diabetes

   • George L. Bakris

   Pages 53-59

6. Hyperlipidemia in Peripheral Arterial Disease

   • Ambika Babu, C. R. Kannan, Theodore Mazzone

   Pages 61-73

7. Hypertension and Peripheral Vascular Disease

   • Anjula Gandhi, Jay Garg, George L. Bakris

   Pages 75-83

8. Physical Inactivity is a Risk Factor for Lower Extremity Arterial Disease and Coronary Heart Disease

   • Dennis G. Caralis, Stamatis Dimitropoulos

   Pages 85-98

9. Pathogenesis of Atherosclerotic Vascular Disease

   • Bassem Jamil Basha, George L. Bakris, James R. Sowers

   Pages 99-181

10. Lower Extremity Arterial Disease Co-Existing With Coronary Artery Disease

    • Dennis G. Caralis

    Pages 183-221

11. Medical Therapy of Claudication and Lower Extremity Arterial Disease

    • Dennis G. Caralis

    Pages 223-242

12. Exercise Therapy for Lower Extremity Arterial Disease

    • Peter F. Kokkinos

    Pages 243-256

13. Endovascular Strategies for Management of Claudication and Lower Extremity Arterial Disease

    • Michael C. Brunner, Dennis G. Caralis

    Pages 257-267

14. Severe Lower Extremity Arterial Disease

    • Chad E. Jacobs, Walter J. McCarthy

    Pages 269-292

15. Back Matter

    Pages 293-306

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A comprehensive review the state-of-the-art in atherosclerosis of the arteries of the legs and feet. The authors discuss in detail the primary symptom-claudication-an intermittent pain in the leg or foot while walking, its predisposing factors, the current diagnostic methodologies, the impressive advances in the therapeutic armamentarium, and the need to screen for co-existing coronary artery disease. Additional chapters describe cutting-edge noninvasive angiography and vascular flow studies, specific drug therapy for claudication, regression of atherosclerosis therapy, gene therapy, and drug eluting stents for peripheral arterial disease. The authors also examine the epidemiology of LEAD, the effects of smoking and effective smoking cessation programs, its pathogenesis and its association with lipid abnormalities and hypertension, aggressive risk factor modification, and the need to measure the ankle brachial index of every patient over 45.

• Diabetes
• Stent
• angiography
• arteries
• atherosclerosis
• coronary artery disease
• diagnosis
• differential diagnosis
• gene therapy
• heart
• hypertension
• management
• pain
• therapy
• vascular disease

"...outstanding...provide(s) guidance for modern physicians on an ancient, but still poorly recognized, group of disorders." - Comprehensive Therapy

• Department of Medicine, Section of Cardiology, Rush University Medical Center, Chicago

  Dennis G. Caralis

• Department of Medicine, Division of Nephrology, Rush University Medical Center, Chicago

  George L. Bakris

Policies and ethics