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Membrane Microdomain Signaling

Lipid Rafts in Biology and Medicine

  • Book
  • © 2005

Overview

Editors:
  1. Mark P. Mattson

    1. Laboratory of Neurosciences, Intramural Research Program, National Institute on Aging, Baltimore
      Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore

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Table of contents (10 chapters)

  1. Front Matter

    Pages i-x
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  2. From Intramolecular Asymmetries to Raft Assemblies

    • Ephraim Yavin, Annette Brand
    Pages 1-14

  3. Regulatory Aspects of Membrane Microdomain (Raft) Dynamics in Live Cells

    • János Matkó, János SzöllÅ‘si
    Pages 15-46

  4. Lipid Raft Membrane Skeletons

    • Elizabeth J. Luna, Thomas Nebl, Norio Takizawa, Jessica L. Crowley
    Pages 47-69

  5. Role of Cholesterol in Membrane Microdomain Signaling

    • Christopher J. Fielding
    Pages 71-89

  6. Raft Lipid Metabolism in Relation to Alkyl-Lysophospholipid-Induced Apoptosis

    • Arnold H. van der Luit, Marcel Verheij, Wim J. van Blitterswijk
    Pages 91-112

  7. The Role of Lipid Rafts in Signal Transduction and Synaptic Plasticity of Neural Cells

    • Markus Delling, Melitta Schachner
    Pages 113-125

  8. Role of Rafts in Virus Fusion and Budding

    • Wu Ou, Jonathan Silver
    Pages 127-142

  9. Alterations in Raft Lipid Metabolism in Aging and Neurodegenerative Disorders

    • Mark P. Mattson, Roy G. Cutler, Norman J. Haughey
    Pages 143-160

  10. Caveolin and Cancer

    • Mordechai Liscovitch, Elke Burgermeister, Neeru Jain, Dana Ravid, Maria Shatz, Lilach Tencer
    Pages 161-190

  11. Dietary Modulation of Lipid Rafts

    • Mark P. Mattson
    Pages 191-201

  12. Back Matter

    Pages 203-214
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Keywords

About this book

Cutting-edge articles review our current understanding of lipid microdomain signaling mechanisms and their physiological and pathological importance. The book describes the role of lipid rafts in learning, memory, and cancer, presents the emerging evidence that lipid rafts play critical roles in signaling pathways and the regulation of synaptic function in the nervous system, and shows how alterations in lipid raft metabolism are implicated in the pathogenesis of neurodegenerative disorders. Techniques are also described for the isolation of lipid rafts, the analysis of the lipid and protein components of lipid rafts, the imaging of lipid rafts in living cells, and the analysis of signal transduction in lipid rafts.

Reviews

"...a good acquisition for general medical and neuroscience libraries." - Doody's Health Science Book Review Journal

Editors and Affiliations

  • Laboratory of Neurosciences, Intramural Research Program, National Institute on Aging, Baltimore

    Mark P. Mattson

  • Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore

    Mark P. Mattson

Bibliographic Information

  • Book Title: Membrane Microdomain Signaling

  • Book Subtitle: Lipid Rafts in Biology and Medicine

  • Editors: Mark P. Mattson

  • DOI: https://doi.org/10.1385/159259803X

  • Publisher: Humana Totowa, NJ

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Humana Press 2005

  • Hardcover ISBN: 978-1-58829-354-1Published: 22 October 2004

  • Softcover ISBN: 978-1-61737-515-6Published: 05 November 2010

  • eBook ISBN: 978-1-59259-803-8Published: 27 October 2007

  • Edition Number: 1

  • Number of Pages: X, 214

  • Topics: Cell Biology

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