Overview
- Editors:
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Gloria H. Su
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Departments of Otolaryngology/Head and Neck Surgery and Pathology, Columbia University, New York
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Table of contents (20 protocols)
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- Ralph H. Hruban, Robb E. Wilentz, Anirban Maitra
Pages 1-13
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- G. Steven Bova, Isam A. Eltoum, John A. Kiernan, Gene P. Siegal, Andra R. Frost, Carolyn J. M. Best et al.
Pages 15-66
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- Robb E. Wilentz, Ayman Rahman, Pedram Argani, Christine Iacobuzio-Donahue
Pages 67-88
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- Helen L. Fedor, Angelo M. De Marzo
Pages 89-101
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- Kimberly Walter, James Eshleman, Michael Goggins
Pages 103-111
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- Terence Lawson, Michel Ouellette, Carol Kolar, Michael Hollingsworth
Pages 113-122
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- Carmelle D. Curtis, Michael Goggins
Pages 123-136
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- Hsueh-Wei Chang, Ie-Ming Shih
Pages 137-141
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- Antoinette Hollestelle, Mieke Schutte
Pages 143-159
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- David E. Misek, Rork Kuick, Samir M. Hanash, Craig D. Logsdon
Pages 175-187
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- Christophe Rosty, Michael Goggins
Pages 189-197
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- Kazuhiro Mizumoto, Masao Tanaka
Pages 199-205
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- Yao-Tseng Chen, Ali O. Gure, Matthew J. Scanlan
Pages 207-216
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- Paul J. Grippo, Eric P. Sandgren
Pages 217-243
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- Julie R. Jones, Kathy D. Shelton, Mark A. Magnuson
Pages 245-257
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- Farzad Esni, Yoshiharu Miyamoto, Steven D. Leach, Bidyut Ghosh
Pages 259-271
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- Nelson S. Yee, Michael Pack
Pages 273-298
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- Dan Laheru, Barbara Biedrzycki, Amy M. Thomas, Elizabeth M. Jaffee
Pages 299-327
About this book
Pancreatic ductal adenocarcinoma is the fourth leading cause of cancer death in the United States. Annually approximately 30,000 Americans are diagnosed with the disease and most will die from it within five years. P- creatic ductal adenocarcinoma is unique because of its late onset in age, high mortality, small tumor samples infiltrated with normal cells, and a lack of both early detection and effective therapies. Some of these characteristics have made studying this disease a challenge. Pancreatic cancer develops as a result of the accumulation of genetic alterations in cancer-causing genes, such as the oncogenes and the tumor-s- pressor genes. In the last decade, major progress has been made in identifying important oncogenes and tumor-suppressor genes for the disease. In Panc- atic Cancer: Methods and Protocols, we review the classical techniques that have contributed to the advances in pancreatic research and introduce new strategies that we hope will add to future breakthroughs in the field of cancer biology. Pancreatic Cancer: Methods and Protocols provides a broad range of protocols for molecular, cellular, pathological, and statistical analyses of s- radic and familial pancreatic cancer. It covers topics from in vitro cell c- tures to in vivo mouse models, DNA to protein manipulation, and mutation analyses to treatment development. We believe that our book will prove an invaluable source of proven protocols for those who are interested in either basic or translational research in pancreatic cancer.
Reviews
"...a worthwhile contribution from a team of experts." Doody's Health Sciences and Book Review Journal
"...a welcome addition to the field...an excellent collection of protocols for a broad range of advanced techniques relevant to many aspects of pancreatic cancer research." -Karger
Editors and Affiliations
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Departments of Otolaryngology/Head and Neck Surgery and Pathology, Columbia University, New York
Gloria H. Su