Overview
- Editors:
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Thomas J. Steinbach
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North Carolina Laboratory, Experimental Pathology Laboratories, Inc., Durham, USA
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Daniel J. Patrick
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Charles River Laboratories, Inc., Mattawan, USA
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Mary Ellen Cosenza
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MEC Regulatory and Toxicology Consulting, LLC, Moorpark, USA
Provides practical guidance for non-pathologists in the complex field of pathology
Based on a successful course supported by the ACT and STP
Serves as a tool for aiding toxicologists to converse in the language of pathology
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Table of contents (21 chapters)
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- Ted A. Birkebak, Peter C. Mann
Pages 45-77
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- Pamela Blackshear, Erica Carroll, Sasmita Mishra, Matthew Renninger, Arun Tatiparthi
Pages 79-112
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- Robert R. Maronpot, David E. Malarkey
Pages 113-136
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- Mark J. Hoenerhoff, Arun Kumar R. Pandiri
Pages 137-199
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- Juliana S. Lee, Sarah D. Cramer, Mark T. Butt
Pages 251-277
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- Joshua H. Decker, Radhakrishna Sura, Paul W. Snyder
Pages 279-309
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- Jack R. Harkema, James G. Wagner
Pages 311-354
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- Tracey L. Papenfuss, Marlon C. Rebelatto, Brad Bolon
Pages 355-395
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- Kelly L. Diegel, Lars Mecklenburg, Lydia Andrews-Jones, David F. Adams
Pages 483-535
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- Brent E. Walling, Thomas J. Rosol
Pages 537-569
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- Stacey L. Fossey, D. Greg Hall, Andrew W. Suttie, Martin Guillot, Aurore Varela
Pages 571-618
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- Adam Aulbach, Laura Cregar
Pages 689-743
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- Catherine A. Picut, Amera K. Remick
Pages 779-849
About this book
This extensive volume began as a short course primarily geared toward toxicologists who want to expand their understanding of toxicologic pathology in order to be better study directors while also proving to be of great interest to other drug development scientists and regulatory reviewers. The overall goal is to help non-pathologists understand, contextualize, and communicate the pathology data and interpretations from the study pathologist in a practical and usable format. Within the book, readers will find an overview of general pathology concepts that include fundamental vocabulary and the basics of pathophysiological processes, along with numerous chapters devoted to pathology in specific organ systems as well as topics such as biomarkers, correlation of clinical pathology endpoints (chemistry and hematology) with microscopic changes, and well-known pathology findings for classes of toxic substances.
Authoritative, practical, and comprehensive, Toxicologic Pathology for Non-Pathologists aims to help non-pathologists understand, converse in, and apply a basic understanding of pathology in their day-to-day careers.
Editors and Affiliations
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North Carolina Laboratory, Experimental Pathology Laboratories, Inc., Durham, USA
Thomas J. Steinbach
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Charles River Laboratories, Inc., Mattawan, USA
Daniel J. Patrick
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MEC Regulatory and Toxicology Consulting, LLC, Moorpark, USA
Mary Ellen Cosenza
About the editors
Thomas J. Steinbach DVM, DACVP, DABT (Experimental Pathology Laboratories, Inc., Research Triangle Park, NC, USA) and Daniel J. Patrick DVM, DACVP, DABT (Charles River Laboratories, Inc., Mattawan, MI, USA) have worked for numerous years to help organize the successful "Pathology for Non-Pathologists" short course, created with the support of the American College of Toxicology (ACT) and Society of Toxicologic Pathology (STP), upon which this book is based. Mary Ellen Cosenza PhD, DABT, RAC, ATS (MEC Regulatory & Toxicology Consulting, LLC, Moorpark, CA, USA) was an inaugural committee member of this short course and remains a highly respected member of the community at large.
