Overview
- Includes cutting-edge methods and protocols
- Provide step-by-step detail essential for reproducible results
- Contains key notes and implementation advice from the experts
Part of the book series: Methods in Molecular Biology (MIMB, volume 1891)
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Table of contents (19 protocols)
Keywords
About this book
This volume provides methods to study bone morphogenetic proteins (BMPs) and BMP modulators in cell culture, in both invertebrate and vertebrate animal models, and for therapeutic applications. Chapters guide the reader in the use of primary and immortalized cell lines, methodologies that exploit transcription and receptor mechanisms, newly developed animal models using nematodes, flies, amphioxus, frogs, zebrafish, and genetically engineered mice, and pre-clinical approaches to understanding BMP function in bone regeneration, heterotopic ossification, and cancers. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls.
Authoritative and cutting-edge, Bone Morphogenetic Proteins: Methods and Protocols aims to ensure successful results in the further study of this vital field.
Editors and Affiliations
Bibliographic Information
Book Title: Bone Morphogenetic Proteins
Book Subtitle: Methods and Protocols
Editors: Melissa B. Rogers
Series Title: Methods in Molecular Biology
DOI: https://doi.org/10.1007/978-1-4939-8904-1
Publisher: Humana New York, NY
eBook Packages: Springer Protocols
Copyright Information: Springer Science+Business Media, LLC, part of Springer Nature 2019
Hardcover ISBN: 978-1-4939-8903-4Published: 10 November 2018
eBook ISBN: 978-1-4939-8904-1Published: 09 November 2018
Series ISSN: 1064-3745
Series E-ISSN: 1940-6029
Edition Number: 1
Number of Pages: XII, 265
Number of Illustrations: 10 b/w illustrations, 27 illustrations in colour
Topics: Molecular Medicine