Editors:
- Includes cutting-edge methods and protocols
- Provides step-by-step detail essential for reproducible results
- Contains key notes and implementation advice from the experts
Part of the book series: Methods in Molecular Biology (MIMB, volume 1856)
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Table of contents (18 protocols)
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Front Matter
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Early Epigenetic Changes and New Epigenetic Targets in Different Types of Cancers
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Front Matter
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Contributing Environmental Factors to Epigenetic Changes Leading to Cancer Development
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Front Matter
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Methods Used in Cancer Epigenomics
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Front Matter
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About this book
This volume discusses certain epigenetic changes recognized in early carcinogenic lesions and different tumors, as well as factors that alter the epigenome and epigenetic profile such as diet, alcohol, immunity, circadian rhythm, and more. The chapters in this book further delve into this field and cover topics such as epigenome-based precision medicine in lung cancer; interplay between genetic and epigenetic changes in breast cancer subtypes; genetic regulation of PDCD1 gene in cancer immunology; and pyrosequencing methylation analysis. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Cutting-edge and authoritative, Cancer Epigenetics for Precision Medicine: Methods and Protocols is a valuable resource to help researchers and scientists identify these specific biomarkers and work towards the prevention, diagnosis, and prognosis of different cancers in the future.
Editors and Affiliations
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Kelly Government Solutions, Bethesda, USA
Ramona G. Dumitrescu
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Division of Cancer Control and Population Sciences, National Cancer Institute, National Institutes of Health, Bethesda, USA
Mukesh Verma
Bibliographic Information
Book Title: Cancer Epigenetics for Precision Medicine
Book Subtitle: Methods and Protocols
Editors: Ramona G. Dumitrescu, Mukesh Verma
Series Title: Methods in Molecular Biology
DOI: https://doi.org/10.1007/978-1-4939-8751-1
Publisher: Humana New York, NY
eBook Packages: Springer Protocols
Copyright Information: Springer Science+Business Media, LLC, part of Springer Nature 2018
Hardcover ISBN: 978-1-4939-8750-4Published: 03 September 2018
Softcover ISBN: 978-1-4939-9383-3Published: 27 November 2019
eBook ISBN: 978-1-4939-8751-1Published: 03 September 2018
Series ISSN: 1064-3745
Series E-ISSN: 1940-6029
Edition Number: 1
Number of Pages: X, 298
Number of Illustrations: 2 b/w illustrations, 12 illustrations in colour
Topics: Cancer Research