Editors:
- Includes cutting-edge methods and protocols
- Provides step-by-step detail essential for reproducible results
- Contains key notes and implementation advice from the experts
Part of the book series: Methods in Molecular Biology (MIMB, volume 1840)
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Table of contents (22 protocols)
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Front Matter
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Structural and Biochemical Analysis of LINC Complexes
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Front Matter
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Mechanical Aspects of the LINC Complex
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Front Matter
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Analysis of the LINC Complex in Model Systems and Development
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Front Matter
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About this book
This volume describes research methodologies and approaches used to study the Linker of Nucleoskeleton and Cytoskeleton (LINC) complex and its cellular functions. Chapters detail structural and biochemical analysis of LINC complexes, mechanical aspects of the LINC complex, analysis of the LINC complex in model systems and development, and LINC complex in mammalian tissue, organs, and disease. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Authoritative and cutting-edge, The LINC Complex: Methods and Protocols aims to ensure successful results in the further study of this vital field.
Editors and Affiliations
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Department of Pathology and Cell Biology, Columbia University, New York, USA
Gregg G. Gundersen
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Department of Medicine and Department of Pathology and Cell Biology, Columbia University, New York, USA
Howard J. Worman
Bibliographic Information
Book Title: The LINC Complex
Book Subtitle: Methods and Protocols
Editors: Gregg G. Gundersen, Howard J. Worman
Series Title: Methods in Molecular Biology
DOI: https://doi.org/10.1007/978-1-4939-8691-0
Publisher: Humana New York, NY
eBook Packages: Springer Protocols
Copyright Information: Springer Science+Business Media, LLC, part of Springer Nature 2018
Hardcover ISBN: 978-1-4939-8690-3Published: 24 August 2018
Softcover ISBN: 978-1-4939-9367-3Published: 10 December 2019
eBook ISBN: 978-1-4939-8691-0Published: 23 August 2018
Series ISSN: 1064-3745
Series E-ISSN: 1940-6029
Edition Number: 1
Number of Pages: XIV, 338
Number of Illustrations: 20 b/w illustrations, 41 illustrations in colour
Topics: Cell Biology