Psychoneuroimmunology

1. Front Matter

   Pages i-xi

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2. Stress and Immunity: Biopsychosocial Models and Clinical Implications

   1. Front Matter

      Pages 1-1

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   2. Stress and Systemic Inflammation: Yin-Yang Dynamics in Health and Diseases

      • Qing Yan

      Pages 3-20

   3. Intersections Between Neuroimmune and Microbiota

      • Colette G. Ngo Ndjom, Xavier F. Gonzalez, Harlan P. Jones

      Pages 21-35

   4. Psychoneuroimmunology: The Experiential Dimension

      • Elling Ulvestad

      Pages 37-53

   5. Ecological Context and Human Variation: Applying the Principles of Biological Anthropology to Psychoneuroimmunology

      • Eric C. Shattuck

      Pages 55-76

   6. Neuroimmune Imbalances and Yin-Yang Dynamics in Stress, Anxiety, and Depression

      • Qing Yan

      Pages 77-85

   7. Increasing Resilience to Traumatic Stress: Understanding the Protective Role of Well-Being

      • J. Tory Toole, Mark A. Rice Jr, Jordan Cargill, Travis J. A. Craddock, Barry Nierenberg, Nancy G. Klimas et al.

      Pages 87-100

   8. Exploring the Diagnostic Potential of Immune Biomarker Co-expression in Gulf War Illness

      • Gordon Broderick, Mary Ann Fletcher, Michael Gallagher, Zachary Barnes, Suzanne D. Vernon, Nancy G. Klimas

      Pages 101-120

   9. Breaking Away: The Role of Homeostatic Drive in Perpetuating Depression

      • J. Tory Toole, Mark A. Rice Jr, Travis J. A. Craddock, Barry Nierenberg, Nancy G. Klimas, Mary Ann Fletcher et al.

      Pages 121-144

   10. Neuroimmune Mechanisms of Depression in Adults with Heart Failure

       • Jessica A. Jiménez, Christine Tara Peterson, Paul J. Mills

       Pages 145-169

   11. How to Monitor the Neuroimmune Biological Response in Patients Affected by Immune Alteration-Related Systemic Diseases

       • Paolo Lissoni, Franco Rovelli, Luigi Vigorè, Giusy Messina, Arianna Lissoni, Giorgio Porro et al.

       Pages 171-191

3. Technologies and Methods in Psychoneuroimmunology Studies

   1. Front Matter

      Pages 193-193

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   2. Application of Chemogenetics and Optogenetics to Dissect Brain-Immune Interactions

      • Ben Korin, Asya Rolls

      Pages 195-208

   3. Psychoneuroimmunology and Natural Killer Cells: The Chromium-Release Whole-Blood Assay

      • Mary Ann Fletcher, Zachary Barnes, Gordon Broderick, Nancy G. Klimas

      Pages 209-220

   4. Mouse Testing Methods in Psychoneuroimmunology 2.0: Measuring Behavioral Responses

      • Albert E. Towers, Jason M. York, Tracy Baynard, Stephen J. Gainey, Gregory G. Freund

      Pages 221-258

   5. The MRL Model: A Valuable Tool in Studies of Autoimmunity-Brain Interactions

      • Boris Šakić

      Pages 259-285

   6. PET Imaging in Psychoneuroimmunology Research

      • Jonas Hannestad

      Pages 287-307

   7. The Vaccination Model in Psychoneuroimmunology Research: A Review

      • Anna C. Whittaker

      Pages 309-326

   8. Measuring Vaccine Responses in the Multiplex Era

      • Kieran Ayling, Kavita Vedhara, Lucy Fairclough

      Pages 327-340

This fully-updated book provides systems-based methodologies and innovative technologies that can be used for solving complicated problems of complex systems. A wide range of theoretical and experimental approaches are introduced for practical applications, as the content explores the basic and novel concepts in psychoneuroimmunology (PNI), especially the relationships among stress, inflammation, and psychophysiological disorders, as well as various cutting-edge technologies and methods for PNI studies, including the utilizations of mouse models and vaccine models. In addition, this book focuses on translational medicine by applying PNI methods in clinical practice. As part of the Methods in Molecular Biology series, the chapters seek to provide a practical, state-of-the-art, and holistic view for the translation of PNI into better preventive and personalized medical practice. 

Authoritative and hands-on, Psychoneuroimmunology: Methods and Protocols, Second Edition will be of use to biomedical students and professionals at all levels who are interested in integrative studies in psychology, psychiatry, neuroscience, immunology, molecular biology, genetics, bioengineering, physiology, pathology, microbiology, systems biology, and clinical medicine.

• Personalized Medicine
• Biopsychosocial models
• Systems medicine
• Therapeutics
• Clinical implications
• PNI
• Stress

• University of Maryland University College, Adelphi, MD, PharmTao, Santa Clara, USA

  Qing Yan

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