Brain Morphometry

1. Front Matter

   Pages i-xvi

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2. Brain Morphometry: Methods

   1. Front Matter

      Pages 1-1

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   2. Registration

      • Anand A. Joshi

      Pages 3-12

   3. Convolutional Neural Networks for Rapid and Simultaneous Brain Extraction and Tissue Segmentation

      • Nicholas C. Cullen, Brian B. Avants

      Pages 13-34

   4. Cortical Thickness

      • Konrad Wagstyl, Jason P. Lerch

      Pages 35-49

   5. Surface and Shape Analysis

      • Robert Dahnke, Christian Gaser

      Pages 51-73

   6. The General Linear Model: Theory and Practicalities in Brain Morphometric Analyses

      • Cyril R. Pernet

      Pages 75-85

3. Brain Morphometry: Non Clinical Applications

   1. Front Matter

      Pages 87-87

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   2. Relating High-Dimensional Structural Networks to Resting Functional Connectivity with Sparse Canonical Correlation Analysis for Neuroimaging

      • Brian B. Avants

      Pages 89-104

   3. Source-Based Morphometry: Data-Driven Multivariate Analysis of Structural Brain Imaging Data

      • Cota Navin Gupta, Jessica A. Turner, Vince D. Calhoun

      Pages 105-120

   4. Integrating Cytoarchitectonic Probabilities with MRI-Based Signal Intensities to Calculate Regional Volumes of Interest

      • Florian Kurth, Lutz Jancke, Eileen Luders

      Pages 121-129

   5. Morphometry of the Corpus Callosum

      • Eileen Luders, Paul M. Thompson, Florian Kurth

      Pages 131-142

   6. Morphometry and Development: Changes in Brain Structure from Birth to Adult Age

      • Christian K. Tamnes, Ylva Østby

      Pages 143-164

   7. Morphometry in Normal Aging

      • Hiroshi Matsuda

      Pages 165-181

   8. Morphometry and Genetics

      • Ali Bani-Fatemi, Samia Tasmim, Tayna Santos, Jose Araujo, Vincenzo De Luca

      Pages 183-202

   9. Multicenter Studies of Brain Morphometry

      • Fabrizio Piras, Mariangela Iorio, Daniela Vecchio, Tommaso Gili, Federica Piras, Gianfranco Spalletta

      Pages 203-214

4. Brain Morphometry: Clinical Applications

   1. Front Matter

      Pages 215-215

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   2. Brain Morphometry: Alzheimer’s Disease

      • Matteo De Marco, Annalena Venneri

      Pages 217-240

   3. Structural MRI in Neurodegenerative Non-Alzheimer’s Dementia

      • Margherita Di Paola, Ali K. Bourisly

      Pages 241-265

   4. Brain Morphometry: Parkinson’s Disease

      • Patrice Péran, Federico Nemmi, Gaetano Barbagallo

      Pages 267-277

This volume presents the latest methods and approaches used to better characterize the properties of the structural human brain, and also explores various dysfunctional and non-dysfunctional neuroanatomical variations. This book is divided into 3 parts: methods, non-clinical applications, and clinical applications. The chapters in Part 1 talk about methods to study cortical thickness and the general linear model. Part 2 covers changes in brain structure from birth to adulthood, and morphometry of the corpus callosum. Part 3 discusses applications to study Alzheimer’s Disease, Parkinson’s Disease, epilepsy, Schizophrenia, and suicide. In Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory.



Cutting-edge and comprehensive, Brain Morphometry is a valuable resource for students, clinicians, and researchers who are interested in this developingfield.

• structural human brain
• non-dysfunctional neuroanatomical variations
• corpus callosum
• Alzheimer's Disease
• Parkinson's Disease
• epilepsy
• Schizophrenia
• suicide

• IRCCS Santa Lucia Foundation, Laboratory of Neuropsychiatry, Rome, Italy

  Gianfranco Spalletta

• Division of Neuropsychiatry Menninger Department of Psychiatry and Behavioral Sciences, Baylor College of Medicine, Houston, USA

  Fabrizio Piras

• IMT School for Advanced Studies–Lucca, Lucca, Italy

  Tommaso Gili

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