Editors:
- Includes cutting-edge methods and protocols
- Provides step-by-step detail essential for reproducible results
- Contains key notes and implementation advice from the experts
- Includes supplementary material: sn.pub/extras
Part of the book series: Methods in Molecular Biology (MIMB, volume 1672)
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Table of contents (43 protocols)
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Front Matter
About this book
This volume presents forty-two methods and protocols to analyze diverse aspects of genome instability. Chapters detail mutagenesis and repair, methods to quantify and analyze the properties of DNA double-strand breaks, profile replication, replication proteins strand-specifically, genome instability, fluorescence microscopic techniques, and genomic and proteomic approaches. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Authoritative and cutting-edge, Genome Instability: Methods and Protocols aims to provide a comprehensive resource for the discovery and analysis of the proteins and pathways that are critical for stable maintenance of the genome.
Editors and Affiliations
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Dipartimento di Bioscienze, Università degli Studi di Milano, Milano, Italy
Marco Muzi-Falconi
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Donnelly Centre and Department of Biochemistry, University of Toronto, Toronto, Canada
Grant W Brown
Bibliographic Information
Book Title: Genome Instability
Book Subtitle: Methods and Protocols
Editors: Marco Muzi-Falconi, Grant W Brown
Series Title: Methods in Molecular Biology
DOI: https://doi.org/10.1007/978-1-4939-7306-4
Publisher: Humana New York, NY
eBook Packages: Springer Protocols
Copyright Information: Springer Science+Business Media LLC 2018
Hardcover ISBN: 978-1-4939-7305-7Published: 20 October 2017
Softcover ISBN: 978-1-4939-8447-3Published: 23 August 2018
eBook ISBN: 978-1-4939-7306-4Published: 17 October 2017
Series ISSN: 1064-3745
Series E-ISSN: 1940-6029
Edition Number: 1
Number of Pages: XVI, 663
Number of Illustrations: 33 b/w illustrations, 100 illustrations in colour
Topics: Human Genetics