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Vaccines for Invasive Fungal Infections

Methods and Protocols

  • Book
  • © 2017

Overview

Editors:
  1. Markus Kalkum

    1. Department of Molecular Immunology, Beckman Research Institute of City of Hope, Duarte, USA

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    You can also search for this editor in PubMed   Google Scholar

  2. Margarita Semis

    1. Department of Molecular Immunology, Beckman Research Institute of City of Hope, Duarte, USA

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  • Includes cutting-edge techniques for the study of invasive mycosis vaccine creation and implementation
  • Provides step-by-step detail essential for reproducible results
  • Contains key implementation advice from the experts

Part of the book series: Methods in Molecular Biology (MIMB, volume 1625)

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Table of contents (23 protocols)

  1. Front Matter

    Pages i-xii
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  2. Discovery and Testing of Vaccine Candidates

    1. Front Matter

      Pages 1-1
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    2. Mouse Immunization with Radioattenuated Yeast Cells of Paracoccidioides brasiliensis

      • Estefânia Mara do Nascimento Martins, Antero Silva Ribeiro de Andrade
      Pages 3-21

    3. Heat-Killed Yeast as a Pan-Fungal Vaccine

      • Marife Martinez, Karl V. Clemons, David A. Stevens
      Pages 23-30

    4. Immunoinformatics as a Tool for New Antifungal Vaccines

      • Rupanjali Chaudhuri, Srinivasan Ramachandran
      Pages 31-43

    5. Rational Design of T Lymphocyte Epitope-Based Vaccines Against Coccidioides Infection

      • Brady J. Hurtgen, Chiung-Yu Hung
      Pages 45-64

    6. Identification of Fungal T Cell Epitopes by Mass Spectrometry-Based Proteomics

      • Bernd Roschitzki, Salomé LeibundGut-Landmann
      Pages 65-74

    7. Intranasal Antifungal Vaccination Using DNA-Transfected Dendritic Cells

      • Shanjana Awasthi
      Pages 75-83

    8. DNAhsp65 Vaccine as Therapy against Paracoccidioidomycosis

      • Alice M. Ribeiro, André C. Amaral, Maria Sueli S. Felipe, Anamelia L. Bocca
      Pages 85-96

    9. Idiotypic Antifungal Vaccination: Immunoprotection by Antiidiotypic Antibiotic Antibodies

      • Luciano Polonelli, Walter Magliani, Stefania Conti
      Pages 97-112

    10. Peptide Vaccine Against Paracoccidioidomycosis

      • Carlos P. Taborda, Luiz R. Travassos
      Pages 113-128

    11. Methodology for Anti-Cryptococcal Vaccine Development

      • Ashok K. Chaturvedi, Floyd L. Wormley Jr
      Pages 129-140

  3. Design and Delivery

    1. Front Matter

      Pages 141-141
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    2. Beta-Glucan Particles as Vaccine Adjuvant Carriers

      • Zeynep Mirza, Ernesto R. Soto, Fusun Dikengil, Stuart M. Levitz, Gary R. Ostroff
      Pages 143-157

    3. Th1-Inducing Agents in Prophylaxis and Therapy for Paracoccidioidomycosis

      • Thiago Aparecido da Silva, Fabrício Freitas Fernandes, Taise Natali Landgraf, Ademílson Panunto-Castelo, Maria Cristina Roque-Barreira
      Pages 159-167

    4. Nanoparticle-Based Mycosis Vaccine

      • Swaleha Zubair, Asim Azhar, Nazoora Khan, Ejaj Ahmad, Mohd Ajmal, Mohammad Owais
      Pages 169-211

    5. Yeast Expressing Gp43 Protein as a Vaccine Against Paracoccidioides brasiliensis Infection

      • Aline Ferreira Oliveira, Paulo S. R. Coelho
      Pages 213-224

    6. Vaccination with Phage-Displayed Antigenic Epitope

      • Yicun Wang, Li Wang
      Pages 225-235

    7. Preparation of an Oral Vaccine by Proteome Analysis and Molecular Display Technology

      • Seiji Shibasaki, Mitsuyoshi Ueda
      Pages 237-245

  4. Endpoint Assessment

    1. Front Matter

      Pages 247-247
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Keywords

About this book

This detailed volume focuses on the development of mycosis vaccines via the most common etiological agents of mycoses, such as Aspergillus and Candida species, followed by Cryptococcus, dimorphic fungi, and members of Mucoraceae family of fungi. The book is sectioned into five parts that describe experimental approaches for vaccine candidate discovery, improved vaccine design and delivery, assessment of critical endpoints, analysis of mechanisms of mycosis vaccine protection, and key methods for clinical translation. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting known pitfalls. 

Practical and authoritative, Vaccines for Invasive Fungal Infections: Methods and Protocols provides a standard reference forvaccine researchers, including those who aspire to strengthen their knowledge or desire to acquire a particular technique.


Editors and Affiliations

  • Department of Molecular Immunology, Beckman Research Institute of City of Hope, Duarte, USA

    Markus Kalkum, Margarita Semis

Bibliographic Information

  • Book Title: Vaccines for Invasive Fungal Infections

  • Book Subtitle: Methods and Protocols

  • Editors: Markus Kalkum, Margarita Semis

  • Series Title: Methods in Molecular Biology

  • DOI: https://doi.org/10.1007/978-1-4939-7104-6

  • Publisher: Humana New York, NY

  • eBook Packages: Springer Protocols

  • Copyright Information: Springer Science+Business Media, LLC, part of Springer Nature 2017

  • Hardcover ISBN: 978-1-4939-7103-9Published: 07 June 2017

  • Softcover ISBN: 978-1-4939-8385-8Published: 12 June 2018

  • eBook ISBN: 978-1-4939-7104-6Published: 05 June 2017

  • Series ISSN: 1064-3745

  • Series E-ISSN: 1940-6029

  • Edition Number: 1

  • Number of Pages: XII, 358

  • Number of Illustrations: 20 b/w illustrations, 49 illustrations in colour

  • Topics: Immunology

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