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Recombinant Virus Vaccines

Methods and Protocols

  • Book
  • © 2017

Overview

Editors:
  1. Maureen C. Ferran

    1. Rochester Institute of Technology, Thomas H. Gosnell School of Life Sciences, Rochester, USA

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  2. Gary R. Skuse

    1. Rochester Institute of Technology, Thomas H. Gosnell School of Life Sciences, Rochester, USA

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  • Includes cutting-edge methods and protocols
  • Provides step-by-step detail essential for reproducible results
  • Contains key notes and implementation advice from the experts
  • Includes supplementary material: sn.pub/extras

Part of the book series: Methods in Molecular Biology (MIMB, volume 1581)

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Table of contents (15 protocols)

  1. Front Matter

    Pages i-x
    Download chapter PDF

  2. Double-Stranded DNA Viruses

    1. Front Matter

      Pages 1-1
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    2. Development of Novel Vaccines Against Infectious Diseases Based on Chimpanzee Adenoviral Vector

      • Chao Zhang, Yudan Chi, Dongming Zhou
      Pages 3-13

    3. Development of Recombinant Canarypox Viruses Expressing Immunogens

      • Débora Garanzini, María Paula Del Médico-Zajac, Gabriela Calamante
      Pages 15-28

    4. Fowl Adenovirus-Based Vaccine Platform

      • Juan C. Corredor, Yanlong Pei, Éva Nagy
      Pages 29-54

    5. Development of Recombinant HSV-Based Vaccine Vectors

      • Richard Voellmy, David C. Bloom, Nuria Vilaboa, Joyce Feller
      Pages 55-78

    6. Generating Recombinant Pseudorabies Virus for Use as a Vaccine Platform

      • Feifei Tan, Xiangdong Li, Kegong Tian
      Pages 79-96

    7. Generation and Production of Modified Vaccinia Virus Ankara (MVA) as a Vaccine Vector

      • Vincent Pavot, Sarah Sebastian, Alison V. Turner, Jake Matthews, Sarah C. Gilbert
      Pages 97-119

    8. Poxvirus Safety Analysis in the Pregnant Mouse Model, Vaccinia, and Raccoonpox Viruses

      • Rachel L. Roper
      Pages 121-129

  3. Negative Sense Single-Stranded RNA Viruses

    1. Front Matter

      Pages 131-131
      Download chapter PDF

    2. Development of Recombinant Arenavirus-Based Vaccines

      • Luis Martínez-Sobrido, Juan Carlos de la Torre
      Pages 133-149

    3. Development of Recombinant Measles Virus-Based Vaccines

      • Michael D. Mühlebach, Stefan Hutzler
      Pages 151-168

    4. Recombinant Tri-Segmented Pichinde Virus as a Novel Live Viral Vaccine Platform

      • Rekha Dhanwani, Hinh Ly, Yuying Liang
      Pages 169-179

    5. Human Rhinovirus-A1 as an Expression Vector

      • Khamis Tomusange, Danushka Wijesundara, Eric James Gowans, Branka Grubor-Bauk
      Pages 181-201

    6. Generating Recombinant Vesicular Stomatitis Viruses for Use as Vaccine Platforms

      • John B. Ruedas, John H. Connor
      Pages 203-222

  4. Positive Sense Single-Stranded RNA Viruses

    1. Front Matter

      Pages 223-223
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    2. Alphavirus-Based Vaccines

      • Kenneth Lundstrom
      Pages 225-242

  5. Bacteriophage

    1. Front Matter

      Pages 243-243
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    2. Display of HIV-1 Envelope Protein on Lambda Phage Scaffold as a Vaccine Platform

      • Jonelle L. Mattiacio, Matt Brewer, Stephen Dewhurst
      Pages 245-253

    3. Bacteriophage T4 as a Nanoparticle Platform to Display and Deliver Pathogen Antigens: Construction of an Effective Anthrax Vaccine

      • Pan Tao, Qin Li, Sathish B. Shivachandra, Venigalla B. Rao
      Pages 255-267
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Keywords

About this book

This volume provides readers with methods and protocols for understanding the development of recombinant viruses and their use as vaccines platforms. Recombinant Virus Vaccines: Methods and Protocols details the use of recombinant vaccines that are employed to either produce immunogens in vitro or elicit antibody production in vivo. The chapters in this book are divided into four parts: Part I explores double-stranded DNA viruses; Part II discusses negative sense single-stranded RNA viruses; Part III talks about positive sense single-stranded RNA viruses; and Part IV describes bacteriophages. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

Thorough and cutting-edge, Recombinant Virus Vaccines: Methods and Protocols is a valuable resource for scientists and clinicians who are interested in learning about and adopting methods for use in basic and biomedical research directed toward generating and developing recombinant viral vaccines.

 

Editors and Affiliations

  • Rochester Institute of Technology, Thomas H. Gosnell School of Life Sciences, Rochester, USA

    Maureen C. Ferran, Gary R. Skuse

Bibliographic Information

  • Book Title: Recombinant Virus Vaccines

  • Book Subtitle: Methods and Protocols

  • Editors: Maureen C. Ferran, Gary R. Skuse

  • Series Title: Methods in Molecular Biology

  • DOI: https://doi.org/10.1007/978-1-4939-6869-5

  • Publisher: Humana New York, NY

  • eBook Packages: Springer Protocols

  • Copyright Information: Springer Science+Business Media LLC 2017

  • Hardcover ISBN: 978-1-4939-6867-1Published: 04 April 2017

  • Softcover ISBN: 978-1-4939-8323-0Published: 09 June 2018

  • eBook ISBN: 978-1-4939-6869-5Published: 03 April 2017

  • Series ISSN: 1064-3745

  • Series E-ISSN: 1940-6029

  • Edition Number: 1

  • Number of Pages: X, 273

  • Number of Illustrations: 17 b/w illustrations, 23 illustrations in colour

  • Topics: Immunology

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