Editors:
- Includes cutting-edge methods and protocols
- Provides step-by-step detail essential for reproducible results
- Contains keynotes and implementation advice from the experts
- Includes supplementary material: sn.pub/extras
Part of the book series: Methods in Molecular Biology (MIMB, volume 1561)
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Table of contents (17 protocols)
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Front Matter
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Peptide Docking
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Front Matter
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Prediction and Design of Peptide Binding Specificity
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Front Matter
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Design of Inhibitory Peptides
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Front Matter
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About this book
This volume covers an array of techniques available for studying peptide-protein docking and design. The book is divided into four sections: peptide binding site prediction; peptide-protein docking; prediction and design of peptide binding specificity; and the design of inhibitory peptides. The chapters in Modeling Peptide-Protein Interactions: Methods and Protocols cover topics such as the usage of ACCLUSTER and PeptiMap for peptide binding site prediction; AnchorDock and ATTRACT for blind, flexible docking of peptides to proteins; flexible peptide docking using HADDOCK and FlexPepDock; identifying loop-mediated protein-protein interactions using LoopFinder; and protein-peptide interaction design using PinaColada. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary details for successful application of the different approaches and step-by-step, readily reproducible protocols, as well as tips on troubleshooting and avoiding known pitfalls.
Cutting-edge and thorough, Modeling Peptide-Protein Interactions: Methods and Protocols provides a diverse and unified overview of this rapidly advancing field of major interest and applicability.
Editors and Affiliations
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Microbiology and Molecular Genetics, Hebrew University Hadassah Medical School, Jerusalem, Israel
Ora Schueler-Furman
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Organic Chemistry, The Weizmann Institute of Science, Rehovot, Israel
Nir London
Bibliographic Information
Book Title: Modeling Peptide-Protein Interactions
Book Subtitle: Methods and Protocols
Editors: Ora Schueler-Furman, Nir London
Series Title: Methods in Molecular Biology
DOI: https://doi.org/10.1007/978-1-4939-6798-8
Publisher: Humana New York, NY
eBook Packages: Springer Protocols
Copyright Information: Springer Science+Business Media LLC 2017
Hardcover ISBN: 978-1-4939-6796-4Published: 27 February 2017
Softcover ISBN: 978-1-4939-8302-5Published: 15 July 2018
eBook ISBN: 978-1-4939-6798-8Published: 23 February 2017
Series ISSN: 1064-3745
Series E-ISSN: 1940-6029
Edition Number: 1
Number of Pages: XI, 311
Number of Illustrations: 19 b/w illustrations, 68 illustrations in colour
Topics: Protein Science