Editors:
- Includes cutting-edge methods and protocols
- Provides step-by-step detail essential for reproducible results
- Contains key notes and implementation advice from the experts
Part of the book series: Methods in Molecular Biology (MIMB, volume 1517)
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Table of contents (21 protocols)
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Front Matter
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Reviews
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Front Matter
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Protocols
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Front Matter
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About this book
This volume provides a concise and technical discussion of recently developed approaches to overcome challenges, such as pharmacodynamics and pharmacokinetics difficulties, in miRNA drug discovery. These strategies cover anti-sense agents targeting miRNA that are applied in advanced formulations or are chemically optimized to increase delivery; small molecule miRNA modulators to overcome anti-sense agents’ limitations; general enhancers of miRNA maturation; and Argonaute 2 protein and its pharmacokinetic parameters. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Cutting-edge and thorough, Drug Target miRNA: Methods and Protocols is a valuable resource for anyone interested in the ever-evolving field of miRNA drug discovery.
Editors and Affiliations
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BEROCEUTICA GmbH, Potsdam, Germany
Marco F. Schmidt
Bibliographic Information
Book Title: Drug Target miRNA
Book Subtitle: Methods and Protocols
Editors: Marco F. Schmidt
Series Title: Methods in Molecular Biology
DOI: https://doi.org/10.1007/978-1-4939-6563-2
Publisher: Humana New York, NY
eBook Packages: Springer Protocols
Copyright Information: Springer Science+Business Media, LLC, part of Springer Nature 2017
Hardcover ISBN: 978-1-4939-6561-8Published: 07 December 2016
Softcover ISBN: 978-1-4939-8236-3Published: 06 July 2018
eBook ISBN: 978-1-4939-6563-2Published: 06 December 2016
Series ISSN: 1064-3745
Series E-ISSN: 1940-6029
Edition Number: 1
Number of Pages: XI, 319
Number of Illustrations: 32 b/w illustrations, 62 illustrations in colour
Topics: Pharmacology/Toxicology