Editors:
- Includes cutting-edge methods and protocols involving in silico techniques
- Provides step-by-step detail essential for reproducible results
- Contains key notes and implementation advice from the experts
Part of the book series: Methods in Molecular Biology (MIMB, volume 1425)
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Table of contents (21 protocols)
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Front Matter
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Modeling a Pharmaceutical in the Human Body
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Front Matter
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The Applications of In Silico Models for the Different Endpoints
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Front Matter
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The Scientific and Society Challenges
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Front Matter
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About this book
This detailed volume explores in silico methods for pharmaceutical toxicity by combining the theoretical advanced research with the practical application of the tools. Beginning with a section covering sophisticated models addressing the binding to receptors, pharmacokinetics and adsorption, metabolism, distribution, and excretion, the book continues with chapters delving into models for specific toxicological and ecotoxicological endpoints, as well as broad views of the main initiatives and new perspectives which will very likely improve our way of modelling pharmaceuticals. Written for the highly successful Methods in Molecular Biology series, chapters include the kind of detailed implementation advice that is key for achieving successful research results.
Authoritative and practical, In Silico Methods for Predicting Drug
Toxicity offers the advantage of incorporating data and knowledge from
different fields, such as chemistry, biology, -omics, and pharmacology, to
achieve goals in this vital area of research.
Editors and Affiliations
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Mario Negri Inst for Pharm Rsrch, IRCCS, Milan, Italy
Emilio Benfenati
Bibliographic Information
Book Title: In Silico Methods for Predicting Drug Toxicity
Editors: Emilio Benfenati
Series Title: Methods in Molecular Biology
DOI: https://doi.org/10.1007/978-1-4939-3609-0
Publisher: Humana New York, NY
eBook Packages: Springer Protocols
Copyright Information: Springer Science+Business Media New York 2016
Hardcover ISBN: 978-1-4939-3607-6Published: 17 June 2016
Softcover ISBN: 978-1-4939-8093-2Published: 30 May 2018
eBook ISBN: 978-1-4939-3609-0Published: 16 June 2016
Series ISSN: 1064-3745
Series E-ISSN: 1940-6029
Edition Number: 1
Number of Pages: XI, 534
Number of Illustrations: 37 b/w illustrations, 156 illustrations in colour
Topics: Pharmacology/Toxicology