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  • Reference work
  • © 2016

Neuroscience in the 21st Century

From Basic to Clinical

  • Offers medical students and graduate researchers worldwide a comprehensive introduction and an updated overview of modern neuroscience

  • Encourages the initiation of neuroscience programs in developing countries

  • Edited and authored by leading, international experts in neuroscience and related disciplines

  • Includes supplementary material: sn.pub/extras

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Table of contents (145 entries)

  1. Front Matter

    Pages i-lv
  2. Biophysics

    1. Front Matter

      Pages 1-1
    2. Voltage-Gated Ion Channels

      • Lori Isom, Gustavo Patino, Luis Lopez-Santiago, Yukun Yuan
      Pages 29-59
    3. Ionotropic Glutamate Receptors

      • Rolf Sprengel
      Pages 61-83
    4. Signal Transduction-Dependent Channels

      • Ramon Latorre, Carlos González, Patricio Rojas
      Pages 85-112
  3. Development

    1. Front Matter

      Pages 137-137
    2. Basics of Stem Cell Biology as Applied to the Brain

      • Inna Tabansky, Joel N. H. Stern
      Pages 139-155
    3. Neural Stem Cells in Cerebral Cortex Development

      • Felipe Mora-Bermúdez, Miguel Turrero García, Wieland B. Huttner
      Pages 157-181
    4. Adult Neurogenesis

      • Gerd Kempermann
      Pages 183-200
    5. Axonal Guidance: Making Connections

      • Peter Kozulin, Linda J. Richards
      Pages 201-224
    6. Dendritic Elaboration: Morphology and Chemistry

      • Astrid Rollenhagen, Joachim H. R. Lübke
      Pages 225-264
    7. Regressive Phenomena: Refining Connections

      • Will Agnew-Svoboda, Alex L. Kolodkin, Martin M. Riccomagno
      Pages 265-294
  4. Cell Biology of Neurons and Glia

    1. Front Matter

      Pages 295-295
    2. Dendritic Morphology and Function

      • Roberto Araya
      Pages 297-331
    3. Axonal Transport

      • Anthony Brown
      Pages 333-379
    4. Cell Biology of the Synapse

      • Rochelle S. Cohen
      Pages 381-422
    5. Molecular Regulation of Synaptic Release

      • Reinhard Jahn, Janina Boyken
      Pages 423-474
    6. The Postsynaptic Density

      • Rochelle S. Cohen
      Pages 475-509

About this book

Edited and authored by a wealth of international experts in neuroscience and related disciplines, this key new resource aims to offer medical students and graduate researchers around the world a comprehensive introduction and overview of modern neuroscience.

Neuroscience research is certain to prove a vital element in combating mental illness in its various incarnations, a strategic battleground in the future of medicine, as the prevalence of mental disorders is becoming better understood each year. Hundreds of millions of people worldwide are affected by mental, behavioral, neurological and substance use disorders. The World Health Organization estimated in 2002 that 154 million people globally suffer from depression and 25 million people from schizophrenia; 91 million people are affected by alcohol use disorders and 15 million by drug use disorders. A more recent WHO report shows that 50 million people suffer from epilepsy and 24 million from Alzheimer’s and other dementias.

Because neuroscience takes the etiology of disease—the complex interplay between biological, psychological, and sociocultural factors—as its object of inquiry, it is increasingly valuable in understanding an array of medical conditions. A recent report by the United States’ Surgeon General cites several such diseases: schizophrenia, bipolar disorder, early-onset depression, autism, attention deficit/ hyperactivity disorder, anorexia nervosa, and panic disorder, among many others. Not only is this volume a boon to those wishing to understand the future of neuroscience, it also aims to encourage the initiation of neuroscience programs in developing countries, featuring as it does an appendix full of advice on how to develop such programs. With broad coverage of both basic science and clinical issues, comprising around 150 chapters from a diversity of international authors and including complementary video components, Neuroscience in the 21st Century in its second edition serves as a comprehensive resource to students and researchers alike.

Editors and Affiliations

  • Laboratory of Neurobiology and Behavior, The Rockefeller University, New York, USA

    Donald W. Pfaff

  • National Institute on Drug Abuse (NIDA), National Institutes of Health (NIH), Rockville, USA

    Nora D. Volkow

About the editors

Donald W. Pfaff, Ph.D, is a member of the National Academy of Sciences and a Fellow of the American Academy of Arts and Sciences. His laboratory has published more than 900 research papers and reviews. The author of several books on the brain and behavior, he received the 2005 Award for Excellence in Professional and Scholarly Publishing (medical science category) of the Association of American Publishers for his book, Brain Arousal and Information Theory.

Nora D. Volkow, M.D., is the Director of the US National Institute on Drug Abuse (NIDA) at the National Institutes of Health.  She is a pioneer in the application of modern brain scanning techniques to the mechanisms of the addictive disorders so problematic to medicine and public health.  Her approaches are not limited to reward processes in the basal forebrain, and also include consideration of behavioral regulation by the prefrontal cortex.

Bibliographic Information

  • Book Title: Neuroscience in the 21st Century

  • Book Subtitle: From Basic to Clinical

  • Editors: Donald W. Pfaff, Nora D. Volkow

  • DOI: https://doi.org/10.1007/978-1-4939-3474-4

  • Publisher: Springer New York, NY

  • eBook Packages: Biomedical and Life Sciences, Reference Module Biomedical and Life Sciences

  • Copyright Information: Springer Science+Business Media New York 2016

  • eBook ISBN: 978-1-4939-3474-4Published: 26 October 2016

  • Edition Number: 2

  • Number of Pages: LV, 4155

  • Number of Illustrations: 281 b/w illustrations, 1013 illustrations in colour

  • Topics: Neurosciences, Neurobiology, Neurology

Buy it now

Buying options

eBook USD 2,999.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever

Tax calculation will be finalised at checkout

Other ways to access