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  • Book
  • © 2016

Circadian Clocks: Role in Health and Disease

  • Updates readers on new findings concerning the essential role of biological rhythms
  • Addresses both basic research and clinical aspects
  • Written by leading scientists and clinicians

Part of the book series: Physiology in Health and Disease (PIHD)

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Table of contents (12 chapters)

  1. Front Matter

    Pages i-vi
  2. Circadian Regulation of Sleep

    • Kazuo Mishima
    Pages 103-115
  3. Circadian Regulation of Renal Function

    • Kristen Solocinski, Gianluigi Mazzoccoli, Michelle L. Gumz
    Pages 175-198
  4. The Cardiac Clock

    • Faisal J. Alibhai, Elena V. Tsimakouridze, Cristine J. Reitz, W. Glen Pyle, Tami A. Martino
    Pages 225-250
  5. Regulation of Immunity by the Circadian Clock

    • Alba de Juan, David Druzd, Louise Ince, Christoph Scheiermann
    Pages 251-266
  6. Rhythms in the Digestive System

    • David B. Rhoads, Lynne L. Levitsky, Ali Tavakkoli
    Pages 267-293
  7. Chronotherapy of Blood Pressure Medications to Improve Management of Hypertension and Reduce Vascular Risk

    • Ramón C. Hermida, Diana E. Ayala, Michael H. Smolensky, Francesco Portaluppi
    Pages 295-334
  8. The Circadian Clock as a Drug Target

    • Sadichha Situala, Ariadna Amador, Thomas P. Burris
    Pages 335-366
  9. Back Matter

    Pages 367-378

About this book

This book sheds new light on the molecular mechanisms that generate circadian rhythms. It examines how biological rhythms influence physiological processes such as sleep, hormone synthesis and secretion, immunity, kidney function, the cardiovascular system, blood pressure, and the digestive system. Clinical implications are considered while exploring the impact of rhythms on neuropsychiatric disorders and chronotherapy’s potential for reducing cardiovascular risk. Offering a cross-section of expertise in both basic and translational (bench-to-bedside) research, this book serves as a guide for physicians and scientists who wish to learn more about the impact of circadian rhythms on physiological processes in health and disease. 

Reviews

“The audience is scientists or students interested in the role circadian clocks play in modulating the functions of physiological systems. … This is a high quality, comprehensive treatment of a very complex field of physiology. It is written in a logical, understandable manner that makes it easier to comprehend difficult topics. … Doctoral students in physiology will find their understanding of homeostasis and human survival enhanced by this book. It is an excellent contribution to the field of physiology.” (David R. Bell, Doody's Book Reviews, August, 2016)

Editors and Affiliations

  • University of Florida, Gainesville, USA

    Michelle L. Gumz

About the editor

Michelle L. Gumz, Ph.D., Assistant Professor, University of Florida, Department of Medicine, Division of Nephrology, Hypertension and Renal Transplantation, Gainesville FL, USA

Bibliographic Information

Buy it now

Buying options

eBook USD 99.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 129.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 179.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access