Editors:
- Includes cutting-edge methods and protocols for the study of RNA imaging
- Provides step-by-step detail essential for reproducible results
- Contains key notes and implementation advice from the experts
Part of the book series: Methods in Molecular Biology (MIMB, volume 1372)
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Table of contents (16 protocols)
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Front Matter
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Back Matter
About this book
This detailed volume will focus on the phenomenon of RNA interference by providing comprehensive coverage of various techniques for in vivo micro/siRNA imaging including the design and synthesis of specific imaging agents and tools, the development of imaging methodologies, and their interpretation. An essential element in the development and optimization of these therapies is the ability to measure the bioavailability and functionality of the RNA/oligonucleotide molecule after administration into the body. Noninvasive imaging provides the necessary set of tools to accomplish this in authentic physiologic environments and across time. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Authoritative and practical, RNA Imaging: Methods and Protocols serves physicians, scientists, and graduate students who are either new to the field of RNA-based imaging and its associated therapeutic applications or who wish to be apprised of recent advances in the state of the art.
Editors and Affiliations
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Massachusetts General Hospital, Charlestown, USA
Zdravka Medarova
Bibliographic Information
Book Title: RNA Imaging
Book Subtitle: Methods and Protocols
Editors: Zdravka Medarova
Series Title: Methods in Molecular Biology
DOI: https://doi.org/10.1007/978-1-4939-3148-4
Publisher: Humana New York, NY
eBook Packages: Springer Protocols
Copyright Information: Springer Science+Business Media New York 2016
Hardcover ISBN: 978-1-4939-3147-7
Softcover ISBN: 978-1-4939-4974-8
eBook ISBN: 978-1-4939-3148-4
Series ISSN: 1064-3745
Series E-ISSN: 1940-6029
Edition Number: 1
Number of Pages: XI, 218
Topics: Imaging / Radiology, Gene Expression