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Macro-Glycoligands

Methods and Protocols

  • Book
  • © 2016

Overview

Editors:
  1. Xue-Long Sun

    1. Cleveland State University, Cleveland, USA

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  • Includes cutting-edge methods and protocols
  • Provides step-by-step detail essential for reproducible results
  • Contains key notes and implementation advice from the experts

Part of the book series: Methods in Molecular Biology (MIMB, volume 1367)

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Table of contents (17 protocols)

  1. Front Matter

    Pages i-xiii
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  2. Synthesis and Characterization of Glycopolymers

    1. Front Matter

      Pages 1-1
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    2. Synthesis of Chain-End Functionalized Glycopolymers via Cyanoxyl-Mediated Free Radical Polymerization (CMFRP)

      • Valentinas Gruzdys, Jinshan Tang, Elliot Chaikof, Xue-Long Sun
      Pages 3-12

    3. Protecting-Group-Free Synthesis of Well-Defined Glycopolymers Featuring Negatively Charged Oligosaccharides

      • Luca Albertin
      Pages 13-28

    4. Glycopolymers Prepared by Ring-Opening Metathesis Polymerization Followed by Glycoconjugation Using a Triazole-Forming “Click” Reaction

      • Ronald Okoth, Amit Basu
      Pages 29-37

    5. Protecting-Group-Free Synthesis of Glycopolymers and Their Binding Assay with Lectin and Influenza Virus

      • Tomonari Tanaka, Tadanobu Takahashi, Takashi Suzuki
      Pages 39-48

    6. Carbohydrate-Based Initiators for the Cationic Ring-Opening Polymerization of 2-Ethyl-2-Oxazoline

      • Christine Weber, Michael Gottschaldt, Richard Hoogenboom, Ulrich S. Schubert
      Pages 49-59

    7. Heterofunctional Glycopolypeptides by Combination of Thiol-Ene Chemistry and NCA Polymerization

      • Kai-Steffen Krannig, Helmut Schlaad
      Pages 61-67

    8. Preparation of Proteoglycan Mimetic Graft Copolymers

      • Matt J. Kipper, Laura W. Place
      Pages 69-86

  3. Glycopolymer Nanoparticle Conjugates

    1. Front Matter

      Pages 87-87
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    2. Galactosylated Polymer Nano-objects by Polymerization-Induced Self-Assembly, Potential Drug Nanocarriers

      • Mona Semsarilar, Irene Canton, Vincent Ladmiral
      Pages 89-108

    3. Synthetic Approach to Biotinylated Glyco-Functionalized Quantum Dots: A New Fluorescent Probes for Biomedical Applications

      • Christian K. Adokoh, James Darkwa, Ravin Narain
      Pages 109-121

    4. Surface Modification of Polydivinylbenzene Microspheres with a Fluorinated Glycopolymer Using Thiol-Halogen Click Chemistry

      • Wentao Song, Anthony M. Granville
      Pages 123-135

    5. Glycopolymer-Grafted Polymer Particles for Lectin Recognition

      • Michinari Kohri, Tatsuo Taniguchi, Keiki Kishikawa
      Pages 137-147

    6. Synthesis of Non-spherical Glycopolymer-Decorated Nanoparticles: Combing Thiol-ene with Catecholic Chemistry

      • Xiao Li, Weidong Zhang, Gaojian Chen
      Pages 149-155

    7. Synthetic Approach to Glycopolymer Base Nanoparticle Gold(I) Conjugate: A New Generation of Therapeutic Agents

      • Christian K. Adokoh, James Darkwa, Ravin Narain
      Pages 157-168

    8. Multivalent Glycopolymer-Coated Gold Nanoparticles

      • Sarah-Jane Richards, Caroline I. Biggs, Matthew I. Gibson
      Pages 169-179

  4. Surface Immobilized Glycopolymers

    1. Front Matter

      Pages 181-181
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    2. Modulation of Multivalent Protein Binding on Surfaces by Glycopolymer Brush Chemistry

      • Kai Yu, A. Louise Creagh, Charles A. Haynes, Jayachandran N. Kizhakkedathu
      Pages 183-193

    3. Oriented Immobilized Sialyloligo-macroligand Microarray

      • Satya Nandana Narla, Xue-Long Sun
      Pages 195-206
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Keywords

About this book

This volume details methods and protocols for the synthesis and characterization of glycopolymers and their biomedical applications. Chapters are divided into three parts covering synthesis and characterization of glycopolymers; glycopolymer-nanoparticle conjugates; and surface immobilized glycopolymers.  Written for the Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

Authoritative and practical, Macro-Glycoligands: Methods and Protocols aims to ensure successful results in the further study of this vital field.

Editors and Affiliations

  • Cleveland State University, Cleveland, USA

    Xue-Long Sun

Bibliographic Information

  • Book Title: Macro-Glycoligands

  • Book Subtitle: Methods and Protocols

  • Editors: Xue-Long Sun

  • Series Title: Methods in Molecular Biology

  • DOI: https://doi.org/10.1007/978-1-4939-3130-9

  • Publisher: Humana New York, NY

  • eBook Packages: Springer Protocols

  • Copyright Information: Springer Science+Business Media New York 2016

  • Hardcover ISBN: 978-1-4939-3129-3Published: 08 November 2015

  • Softcover ISBN: 978-1-4939-4948-9Published: 23 August 2016

  • eBook ISBN: 978-1-4939-3130-9Published: 04 November 2015

  • Series ISSN: 1064-3745

  • Series E-ISSN: 1940-6029

  • Edition Number: 1

  • Number of Pages: XIII, 226

  • Topics: Biochemistry, general

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