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Biosynthesis and Molecular Genetics of Fungal Secondary Metabolites, Volume 2

  • Book
  • © 2015

Overview

Editors:
  1. Susanne Zeilinger

    1. Institute of Chemical Engineering, Vienna University of Technology, Vienna, Austria

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  2. Juan-Francisco Martín

    1. Department of Molecular Biology, University of León, León, Spain

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  3. Carlos García-Estrada

    1. Biomedicine and Biopharma Area (INBIOTEC), Instituto de Biotecnología de León, León, Spain

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  • Up-to-date information on fungal secondary metabolism covering recent advancements in genomics and metabolomics
  • Book chapters written by top scientists, providing a cutting-edge point of view
  • Scientific content appropriate for teaching in the university Interesting also for researchers in industry?
  • Includes supplementary material: sn.pub/extras

Part of the book series: Fungal Biology (FUNGBIO)

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Table of contents (11 chapters)

  1. Front Matter

    Pages i-xi
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  2. Fungal Secondary Metabolites in the “OMICS” Era

    • Susanne Zeilinger, Carlos García-Estrada, Juan-Francisco Martín
    Pages 1-12

  3. Key Players in the Regulation of Fungal Secondary Metabolism

    • Benjamin P. Knox, Nancy P. Keller
    Pages 13-28

  4. Epigenetics of Fungal Secondary Metabolism Related Genes

    • Ming-Yueh Wu, Jae-Hyuk Yu
    Pages 29-42

  5. Genome Mining for Fungal Secondary Metabolic Gene Clusters

    • Grayson T. Wawrzyn, Mark A. Held, Sarah E. Bloch, Claudia Schmidt-Dannert
    Pages 43-65

  6. Metagenomics and Metatranscriptomics for the Exploration of Natural Products from Soil Fungi

    • Irshad Ul Haq, Jan Dirk van Elsas
    Pages 67-79

  7. Metabolomics and Secondary Metabolite Profiling of Filamentous Fungi

    • Bernhard Kluger, Sylvia Lehner, Rainer Schuhmacher
    Pages 81-101

  8. Fungal Chemotaxonomy

    • Jens C. Frisvad
    Pages 103-121

  9. Endophytic Fungi as a Source of Novel Metabolites

    • Fernanda O. Chagas, Andrés Mauricio Caraballo-Rodriguez, Mônica T. Pupo
    Pages 123-176

  10. Fungal Secondary Metabolism in the Light of Animal–Fungus Interactions: From Mechanism to Ecological Function

    • Marko Rohlfs
    Pages 177-198

  11. Fusarium Mycotoxins and Their Role in Plant–Pathogen Interactions

    • Gerhard Adam, Gerlinde Wiesenberger, Ulrich Güldener
    Pages 199-233

  12. Biosynthesis and Molecular Genetics of Peptaibiotics—Fungal Peptides Containing Alpha, Alpha-Dialkyl Amino Acids

    • Xiao-Yan Song, Bin-Bin Xie, Xiu-Lan Chen, Yu-Zhong Zhang
    Pages 235-252

  13. Back Matter

    Pages 253-256
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Keywords

About this book

​Fungi produce many chemically diverse secondary metabolites whose biological roles largely remain elusive. Within the increasing number of sequenced fungal genomes several important genes involved in secondary metabolite formation have been identified. Most of these genes are clustered and their coordinated transcription is controlled in a complex way by both narrow pathway-specific regulators as well as broad global transcription factors responsive to environmental cues. In recent years it was discovered many of the newly identified gene clusters are silent under laboratory conditions suggesting that the biosynthetic potential of fungi is far from being exploited. Besides identifying novel bioactive metabolites from still unexplored sources, the activation of these gene clusters by several approaches may result in the discovery of new substances with antibiotic and pharmaceutical benefits. This book covers recent advances in the field of fungal secondary metabolisms ranging from methodologies to biological aspects and will include the latest knowledge on fungal molecular biology, genomics, and metabolomics. With the related volume by Professor Juan-Francisco Martin, where the most relevant and well-studied fungal secondary metabolites are compiled, this book provides a comprehensive overview of the state-of-the-art of research on fungal secondary metabolites.

Editors and Affiliations

  • Institute of Chemical Engineering, Vienna University of Technology, Vienna, Austria

    Susanne Zeilinger

  • Department of Molecular Biology, University of León, León, Spain

    Juan-Francisco Martín

  • Biomedicine and Biopharma Area (INBIOTEC), Instituto de Biotecnología de León, León, Spain

    Carlos García-Estrada

About the editors

Juan-Francisco Martín, PhD
University of León, Department of Molecular Biology, Area of Microbiology, León, Spain

Carlos García-Estrada, DVM, PhD 
Institute of Biotechnology of León (INBIOTEC), Parque Científico de León, León, Spain

Susanne Zeilinger, PhD
Vienna University of Technology, Institute of Chemical Engineering, Vienna, Austria

Bibliographic Information

  • Book Title: Biosynthesis and Molecular Genetics of Fungal Secondary Metabolites, Volume 2

  • Editors: Susanne Zeilinger, Juan-Francisco Martín, Carlos García-Estrada

  • Series Title: Fungal Biology

  • DOI: https://doi.org/10.1007/978-1-4939-2531-5

  • Publisher: Springer New York, NY

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer Science+Business Media New York 2015

  • Hardcover ISBN: 978-1-4939-2530-8Published: 15 June 2015

  • Softcover ISBN: 978-1-4939-5516-9Published: 13 October 2016

  • eBook ISBN: 978-1-4939-2531-5Published: 15 June 2015

  • Series ISSN: 2198-7777

  • Series E-ISSN: 2198-7785

  • Edition Number: 1

  • Number of Pages: XI, 256

  • Number of Illustrations: 21 b/w illustrations, 14 illustrations in colour

  • Topics: Cell Biology, Microbiology, Plant Genetics and Genomics, Plant Biochemistry

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